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cyclic nucleotide gated channel alpha 3

Summary

Gene Symbol

Cnga3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

12790

PubChem

12790

Alliance of Genome Resources

MGI:1341818

Annotation

Keyword

Calcium channel
Cell membrane
Coiled coil
Glycoprotein
Ligand-gated ion channel
Nucleotide-binding
Reference proteome
Sensory transduction
Sodium channel
Transmembrane helix
Vision
cGMP-binding

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A0A6YXW9
Q9JJZ8	Cone photoreceptor cGMP-gated channel subunit alpha-3 Gustatory cyclic nucleotide-gated cation channel
A0A6H2E2T0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
monoatomic cation transmembrane transport	IBA
monoatomic cation transport	ISO
calcium ion transmembrane transport	IEA
retina development in camera-type eye	IGI	21124780
ion transmembrane transport	ISO

GO Hierarchy

biological process

cellular process [inference]

cellular developmental process [inference]

cell development [inference]

neuron development [inference]

photoreceptor cell development [inference]

eye photoreceptor cell development [inference]

retinal cone cell development

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of light stimulus [inference]

visual perception

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

neuron development [inference]

photoreceptor cell development [inference]

eye photoreceptor cell development [inference]

retinal cone cell development

retina development in camera-type eye

cellular developmental process [inference]

cell development [inference]

neuron development [inference]

photoreceptor cell development [inference]

eye photoreceptor cell development [inference]

retinal cone cell development

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

response to purine-containing compound [inference]

response to cAMP

response to organic cyclic compound [inference]

response to purine-containing compound [inference]

response to cAMP

response to organophosphorus [inference]

response to cAMP

response to inorganic substance [inference]

response to metal ion [inference]

response to magnesium ion

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to purine-containing compound [inference]

response to cAMP

response to oxygen-containing compound [inference]

response to cAMP

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport

metal ion transport [inference]

sodium ion transport [inference]

sodium ion transmembrane transport

calcium ion transport [inference]

calcium ion transmembrane transport

monoatomic cation transmembrane transport

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane

organic substance transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport

import into cell [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
perikaryon	ISO
neuronal cell body	ISO
plasma membrane	IBA IDA ISO	10813773
axon initial segment	ISO
dendrite	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

transmembrane transporter complex

monoatomic ion channel complex [inference]

cation channel complex [inference]

intracellular cyclic nucleotide activated cation channel complex

transporter complex [inference]

transmembrane transporter complex

monoatomic ion channel complex [inference]

cation channel complex [inference]

intracellular cyclic nucleotide activated cation channel complex

cellular anatomical entity [inference]

photoreceptor outer segment

cone photoreceptor outer segment

membrane [inference]

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

glial cell projection

cell body [inference]

neuronal cell body

Displaying entries **6 - 10** of 10 in total

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GO Term	Evidence Code	PMID
calcium channel activity	IEA
intracellular cGMP-activated cation channel activity	IBA ISO
intracellular cAMP-activated cation channel activity	IBA ISO
cadherin binding	ISO
cGMP binding	IBA IEA ISO

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity

ligand-gated monoatomic ion channel activity [inference]

intracellular ligand-gated monoatomic ion channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity

cyclic nucleotide-activated monoatomic ion channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity

ligand-gated monoatomic cation channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

sodium channel activity

calcium ion transmembrane transporter activity [inference]

calcium channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

sodium channel activity

calcium ion transmembrane transporter activity [inference]

calcium channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity

ligand-gated monoatomic ion channel activity [inference]

intracellular ligand-gated monoatomic ion channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity

cyclic nucleotide-activated monoatomic ion channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity

ligand-gated monoatomic cation channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

intracellular ligand-gated monoatomic ion channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity

cyclic nucleotide-activated monoatomic ion channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity

ligand-gated monoatomic cation channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity

salt transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

sodium channel activity

calcium ion transmembrane transporter activity [inference]

calcium channel activity

binding [inference]

protein binding

cytoskeletal protein binding [inference]

myosin binding

cell adhesion molecule binding [inference]

cadherin binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

cGMP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

cGMP binding

cyclic nucleotide binding [inference]

cGMP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

cGMP binding

ion binding [inference]

anion binding [inference]

cGMP binding

protein-containing complex binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

cGMP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

cGMP binding

cyclic nucleotide binding [inference]

cGMP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

cGMP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

cGMP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

cyclic nucleotide-gated cation channel alpha-3

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
cGMP binding
intracellular cAMP-activated cation channel activity
intracellular cGMP-activated cation channel activity
monoatomic ion channel activity
monoatomic ion transport

Displaying **all 6** entries
InterPro
Cyclic nucleotide-binding domain superfamily
Cyclic nucleotide-binding domain
Cyclic nucleotide-binding, conserved site
Cyclic nucleotide-gated channel, C-terminal leucine zipper domain
Ion transport domain
RmlC-like jelly roll fold

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0110007	achromatopsia 2	Alliance of Genome Resources
DOID:13399	color blindness	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of **123** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Sus scrofa	100622548		PIGXX21567
Loxodonta africana	100653571		LOXAF10815
Oreochromis niloticus	100695999		ORENI45497
Cavia porcellus	100712928	10141_0:002c51	CAVPO11361
Cricetulus griseus	100771361	10029_0:000a65	CRIGR04528
Otolemur garnettii	100964792		OTOGA08255
Pan paniscus	100969080		PANPA25350
Papio anubis	101012311		PAPAN10137
Saimiri boliviensis boliviensis	101038194		SAIBB34674
Takifugu rubripes	101062934		TAKRU28822