GlyCosmos Portal

Submissions

ciliary neurotrophic factor receptor

Summary

Gene Symbol

Cntfr

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

12804

PubChem

12804

Alliance of Genome Resources

MGI:99605

Annotation

Keyword

Cell membrane
Disulfide bond
GPI-anchor
Immunoglobulin domain
Receptor
Reference proteome
Repeat
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
O88507

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
brainstem development	IMP	7585948
positive regulation of cell population proliferation	IBA IGI	15051883
suckling behavior	IMP	7585948
skeletal muscle organ development	IMP	10526311
ciliary neurotrophic factor-mediated signaling pathway	IBA IGI ISO	7585948

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

ciliary neurotrophic factor-mediated signaling pathway

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

neuron apoptotic process [inference]

motor neuron apoptotic process

reproductive process [inference]

developmental process involved in reproduction [inference]

sex differentiation

multicellular organismal process [inference]

behavior [inference]

feeding behavior [inference]

suckling behavior

developmental process [inference]

developmental process involved in reproduction [inference]

sex differentiation

anatomical structure development [inference]

brainstem development

animal organ development [inference]

muscle organ development [inference]

skeletal muscle organ development

muscle structure development [inference]

muscle organ development [inference]

skeletal muscle organ development

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of motor neuron apoptotic process

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

ciliary neurotrophic factor-mediated signaling pathway

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of motor neuron apoptotic process

regulation of neuron apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of motor neuron apoptotic process

regulation of motor neuron apoptotic process [inference]

negative regulation of motor neuron apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of motor neuron apoptotic process

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of motor neuron apoptotic process

Displaying **all 5** entries
GO Term	Evidence Code	PMID
external side of plasma membrane	IBA
apical plasma membrane	IEA ISO
side of membrane	IEA
CNTFR-CLCF1 complex	IBA IEA ISO
ciliary neurotrophic factor receptor complex	IBA IEA ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

ciliary neurotrophic factor receptor complex

CNTFR-CLCF1 complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

ciliary neurotrophic factor receptor complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane region [inference]

apical plasma membrane

side of membrane

external side of plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI	15051883
signaling receptor binding	IEA ISO
cytokine receptor activity	IBA
ciliary neurotrophic factor receptor activity	IGI ISO	7585948
cytokine binding	IBA IEA ISO

GO Hierarchy

molecular function

binding [inference]

protein binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity

ciliary neurotrophic factor receptor activity

immune receptor activity [inference]

cytokine receptor activity

ciliary neurotrophic factor receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

ciliary neurotrophic factor receptor subunit alpha

Functional Category

T: Signal transduction mechanisms
X: Mobilome: prophages, transposons

Displaying **all 2** entries
Gene Ontology
ciliary neurotrophic factor receptor activity
cytokine-mediated signaling pathway

Displaying **all 8** entries
InterPro
Fibronectin type III superfamily
Fibronectin type III
Immunoglobulin subtype 2
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold
Long hematopoietin receptor, soluble alpha chain, conserved site

Ortholog

Displaying entries **1 - 10** of 99 in total

1

2

3

4

5

…

Next ›

Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	1271		HGNC:2170	HUMAN96810
Rattus norvegicus	313173	10116_1:001e86	RGD:1303100	RATNO32928
Danio rerio	368438		ZFIN:ZDB-GENE-030616-82	DANRE01286
Canis lupus familiaris	442941			CANLF02259
Pan troglodytes	473218			PANTR43855
Macaca mulatta	700959			MACMU12506
Monodelphis domestica	100028872			MONDO28260
Ornithorhynchus anatinus	100088663			ORNAN18484
Xenopus tropicalis	100135712		Xenbase:XB-GENE-923386
Equus caballus	100146590			HORSE22254