GlyCosmos Portal

Submissions

cartilage oligomeric matrix protein

Summary

Gene Symbol

Comp

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

12845

KEGG Gene ID

PubChem

12845

Alliance of Genome Resources

MGI:88469

Annotation

Keyword

3D-structure
Apoptosis
Calcium
Cell adhesion
Disulfide bond
EGF-like domain
Extracellular matrix
Glycoprotein
Heparin-binding
Phosphoprotein
Reference proteome
Repeat
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9R0G6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 49 in total

1

2

3

4

5

…

Next ›

Last »
GO Term	Evidence Code	PMID
skeletal system development	IGI
ossification	IMP
chondrocyte development	IMP
endochondral bone growth	IMP
growth plate cartilage development	IMP

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cell-cell adhesion [inference]

homotypic cell-cell adhesion [inference]

platelet aggregation

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

BMP signaling pathway

metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein maturation [inference]

protein processing

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein maturation [inference]

protein processing

cell death [inference]

programmed cell death [inference]

apoptotic process

cell population proliferation [inference]

chondrocyte proliferation

cellular developmental process [inference]

cell development [inference]

chondrocyte development

muscle cell development

vascular associated smooth muscle cell development

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

extracellular structure organization [inference]

extracellular matrix organization [inference]

collagen fibril organization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

external encapsulating structure organization [inference]

extracellular matrix organization [inference]

collagen fibril organization

cellular senescence

export from cell [inference]

secretion by cell [inference]

protein secretion

multicellular organismal process [inference]

ossification

system process [inference]

muscle system process [inference]

muscle contraction [inference]

smooth muscle contraction [inference]

vascular associated smooth muscle contraction

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

vasoconstriction [inference]

vascular associated smooth muscle contraction

nervous system process [inference]

neuromuscular process

musculoskeletal movement

multicellular organism growth

organ growth [inference]

bone growth

endochondral bone growth

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

cartilage homeostasis

coagulation [inference]

blood coagulation

multicellular organismal movement [inference]

musculoskeletal movement

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

bone morphogenesis

tube morphogenesis [inference]

blood vessel morphogenesis [inference]

artery morphogenesis

anatomical structure development [inference]

cell development [inference]

chondrocyte development

muscle cell development

vascular associated smooth muscle cell development

system development [inference]

skeletal system development

animal gross anatomical part developmental process [inference]

skeletal system development

tissue development [inference]

biomineral tissue development [inference]

bone mineralization

connective tissue development [inference]

animal organ development [inference]

skin development

cartilage development

cartilage development involved in endochondral bone morphogenesis [inference]

growth plate cartilage development

appendage development [inference]

limb development

cellular developmental process [inference]

cell development [inference]

chondrocyte development

muscle cell development

vascular associated smooth muscle cell development

growth [inference]

developmental growth [inference]

multicellular organism growth

organ growth [inference]

bone growth

endochondral bone growth

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

cartilage homeostasis

response to stimulus [inference]

response to stress [inference]

response to topologically incorrect protein [inference]

response to unfolded protein

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport [inference]

protein secretion

protein localization to extracellular region [inference]

protein secretion

establishment of localization [inference]

transport [inference]

protein transport [inference]

protein secretion

secretion [inference]

secretion by cell [inference]

protein secretion

export from cell [inference]

secretion by cell [inference]

protein secretion

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of chondrocyte proliferation

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of hemostasis

regulation of developmental process [inference]

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

regulation of bone mineralization

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

BMP signaling pathway

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of chondrocyte proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of chondrocyte proliferation

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of multicellular organismal process [inference]

regulation of ossification [inference]

regulation of bone mineralization

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

regulation of bone mineralization

regulation of hemostasis [inference]

negative regulation of hemostasis

regulation of biological quality [inference]

regulation of body fluid levels [inference]

hemostasis [inference]

blood coagulation

regulation of hemostasis [inference]

negative regulation of hemostasis

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

vasoconstriction [inference]

vascular associated smooth muscle contraction

Displaying entries **1 - 5** of 10 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
extracellular region	ISO
extracellular region	IDA
extracellular region	IEA
extracellular region	HDA
obsolete extracellular space

GO Hierarchy

cellular component

protein-containing complex

extracellular protein-containing complex [inference]

thrombospondin complex

cellular anatomical structure [inference]

extracellular region

external encapsulating structure [inference]

extracellular matrix

Displaying entries **1 - 5** of 19 in total

1

2

3

4

Next ›

Last »
GO Term	Evidence Code	PMID
fibronectin binding	ISO
protease binding	ISO
protease binding	IPI
protease binding	IEA
integrin binding	IPI

GO Hierarchy

molecular function

structural molecule activity [inference]

extracellular matrix structural constituent

binding [inference]

protein binding

fibronectin binding

signaling receptor binding [inference]

integrin binding

enzyme binding [inference]

protease binding

cytokine binding [inference]

BMP binding

proteoglycan binding

heparan sulfate proteoglycan binding

cell adhesion molecule binding [inference]

integrin binding

lipid binding [inference]

steroid binding [inference]

vitamin D binding

small molecule binding [inference]

vitamin binding [inference]

vitamin D binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

protein-containing complex binding [inference]

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

proteoglycan binding

heparan sulfate proteoglycan binding

sulfur compound binding [inference]

heparin binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0080047	pseudoachondroplasia	Alliance of Genome Resources
DOID:12721	multiple epiphyseal dysplasia	Alliance of Genome Resources

Ortholog

Displaying **all 3** entries
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	1311	HGNC:2227
Rattus norvegicus	25304	RGD:2378
Drosophila melanogaster	33941	FB:FBgn0031850

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements