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coatomer protein complex subunit alpha

Summary

Gene Symbol

Copa

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

12847

PubChem

12847

Alliance of Genome Resources

MGI:1334462

Annotation

Keyword

3D-structure
Cytoplasm
Cytoplasmic vesicle
ER-Golgi transport
Golgi apparatus
Hormone
Membrane
Methylation
Phosphoprotein
Protein transport
Reference proteome
Repeat
Secreted
WD repeat

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8CIE6	Alpha-coat protein
Q8BTF0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
pancreatic juice secretion	ISO
endoplasmic reticulum to Golgi vesicle-mediated transport	IBA IEA
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	IBA
intracellular protein transport	IBA IEA
intra-Golgi vesicle-mediated transport	IBA

GO Hierarchy

biological process

cellular process [inference]

signal transduction

vesicle-mediated transport [inference]

Golgi vesicle transport [inference]

cellular localization [inference]

intracellular transport [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

multicellular organismal process [inference]

system process [inference]

digestive system process [inference]

pancreatic juice secretion

secretion by tissue [inference]

pancreatic juice secretion

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

Golgi vesicle transport [inference]

secretion [inference]

body fluid secretion [inference]

pancreatic juice secretion

secretion by tissue [inference]

pancreatic juice secretion

intracellular transport [inference]

organic substance transport [inference]

protein transport [inference]

intracellular protein transport

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

cellular localization [inference]

intracellular transport [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction

regulation of biological quality [inference]

regulation of body fluid levels [inference]

body fluid secretion [inference]

pancreatic juice secretion

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
Golgi apparatus	IDA ISO	21300694
neuronal cell body	ISO	21300694
COPI vesicle coat	IBA ISO
COPI-coated vesicle	IDA	21300694 29437892
Golgi membrane	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

membrane coat [inference]

vesicle coat [inference]

COPI vesicle coat

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

site of polarized growth [inference]

growth cone

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

Golgi-associated vesicle [inference]

COPI-coated vesicle

coated vesicle [inference]

COPI-coated vesicle

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

Golgi-associated vesicle [inference]

COPI-coated vesicle

coated vesicle [inference]

COPI-coated vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

Golgi-associated vesicle [inference]

COPI-coated vesicle

coated vesicle [inference]

COPI-coated vesicle

cell body [inference]

neuronal cell body

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein binding	IPI	21300694 36792666
mRNA binding	IDA	21300694
hormone activity	IEA
structural molecule activity	IEA

GO Hierarchy

molecular function

structural molecule activity

binding [inference]

protein binding

signaling receptor binding [inference]

receptor ligand activity [inference]

hormone activity

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding [inference]

mRNA binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

hormone activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

hormone activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

coatomer subunit alpha

Functional Category

L: Replication, recombination and repair
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
intra-Golgi vesicle-mediated transport
structural molecule activity

Displaying **all 10** entries
InterPro
Coatomer subunit alpha, WD Associated Region
Coatomer subunit alpha
Coatomer, WD associated region
Coatomer, alpha subunit, C-terminal
Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily
G-protein beta WD-40 repeat
WD40 repeat, conserved site
WD40 repeat
WD40-repeat-containing domain superfamily
WD40/YVTN repeat-like-containing domain superfamily

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0081242	autoimmune interstitial lung, joint, and kidney disease	Alliance of Genome Resources

Ortholog

Displaying entries **31 - 40** of **122** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Felis catus	101090837		FELCA36821
Ovis aries	101120034		SHEEP01055
Gorilla gorilla gorilla	101134266		GORGO20880
Oryzias latipes	101164093		ORYLA06247
Tursiops truncatus	101329692		TURTR14655
Octodon degus	101592850	10160_0:003447	OCTDE18172
Jaculus jaculus	101609830	51337_0:000afc	JACJA23353
Mustela putorius furo	101682373		MUSPF03420
Heterocephalus glaber	101717477	10181_0:002ef5	HETGA06374
Mesocricetus auratus	101844844	10036_0:004ba9

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OrthoDB (Group)

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Acknowledgements