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ceruloplasmin

Summary

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

12870

PubChem

12870

Alliance of Genome Resources

MGI:88476

Annotation

Keyword

Calcium
Disulfide bond
Glycoprotein
Metal-binding
Oxidoreductase
Proteomics identification
Reference proteome
Repeat
Secreted
Signal
Sodium
Transmembrane helix

Proteins

Displaying **all 5** entries
UniProt	Protein Name
G3X8Q5	Cuproxidase ceruloplasmin Ferroxidase ceruloplasmin Glutathione peroxidase ceruloplasmin Glutathione-dependent peroxiredoxin ceruloplasmin
Q8BU82
E9PZD8	Cuproxidase ceruloplasmin Ferroxidase ceruloplasmin Glutathione peroxidase ceruloplasmin Glutathione-dependent peroxiredoxin ceruloplasmin
Q61147	Cuproxidase ceruloplasmin Ferroxidase ceruloplasmin Glutathione peroxidase ceruloplasmin Glutathione-dependent peroxiredoxin ceruloplasmin
G3X9T8	Cuproxidase ceruloplasmin Ferroxidase ceruloplasmin Glutathione peroxidase ceruloplasmin Glutathione-dependent peroxiredoxin ceruloplasmin

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
liver development	IMP	36261001
intracellular copper ion homeostasis	ISS
intracellular copper ion homeostasis	ISO
intracellular copper ion homeostasis	IMP	36261001
intracellular iron ion homeostasis	ISS

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

organic substance catabolic process [inference]

lipid catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation

primary metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation

lipid metabolic process [inference]

lipid catabolic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance catabolic process [inference]

lipid catabolic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

calcium-mediated signaling [inference]

CAMKK-AMPK signaling cascade

calmodulin dependent kinase signaling pathway [inference]

CAMKK-AMPK signaling cascade

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization

cellular component assembly [inference]

protein-containing complex assembly

protein-containing complex organization [inference]

protein-containing complex assembly

cellular detoxification [inference]

cellular oxidant detoxification

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

gland development [inference]

liver development

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

chemical homeostasis [inference]

carbohydrate homeostasis [inference]

glucose homeostasis

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

copper ion homeostasis [inference]

intracellular copper ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

inorganic ion homeostasis [inference]

intracellular iron ion homeostasis

copper ion homeostasis [inference]

intracellular copper ion homeostasis

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

response to endogenous stimulus [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to organonitrogen compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

response to insulin

response to inorganic substance [inference]

response to metal ion [inference]

response to copper ion

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

response to insulin

response to oxygen-containing compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

response to insulin

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

calcium-mediated signaling [inference]

CAMKK-AMPK signaling cascade

calmodulin dependent kinase signaling pathway [inference]

CAMKK-AMPK signaling cascade

regulation of molecular function [inference]

regulation of binding [inference]

regulation of protein binding

detoxification [inference]

cellular detoxification [inference]

cellular oxidant detoxification

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
extracellular region
extracellular space	ISS
extracellular space	ISO
extracellular space	IDA	16436657
extracellular space	HDA	24006456

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
ferroxidase activity	ISS
ferroxidase activity	ISO
ferroxidase activity	IDA	16436657
glutathione peroxidase activity	ISS
glutathione peroxidase activity	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

oxidoreductase activity, acting on peroxide as acceptor [inference]

peroxidase activity [inference]

oxidoreductase activity, acting on metal ions [inference]

oxidoreductase activity, acting on metal ions, oxygen as acceptor

ferroxidase activity

binding [inference]

protein binding [inference]

protein-folding chaperone binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

copper ion binding

antioxidant activity [inference]

peroxidase activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

hephaestin-like protein

Functional Category

C: Energy production and conversion
P: Inorganic ion transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 3** entries
Gene Ontology
copper ion binding
metal ion binding
oxidoreductase activity

Displaying **all 5** entries
InterPro
Cupredoxin
Multicopper oxidase, C-terminal
Multicopper oxidase, copper-binding site
Multicopper oxidase-like, N-terminal
Multicopper oxidases, conserved site

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050711	aceruloplasminemia	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements