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coproporphyrinogen oxidase

Summary

Gene Symbol

Cpox

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

12892

PubChem

12892

Alliance of Genome Resources

MGI:104841

Annotation

Keyword

Acetylation
Direct protein sequencing
Heme biosynthesis
Mitochondrion
Oxidoreductase
Phosphoprotein
Porphyrin biosynthesis
Reference proteome
Transit peptide

Proteins

Displaying 1 entry
UniProt	Protein Name
P36552

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
protoporphyrinogen IX biosynthetic process	ISO
protoporphyrinogen IX biosynthetic process	IBA
protoporphyrinogen IX biosynthetic process	IEA
heme biosynthetic process	ISO
heme biosynthetic process	IDA	8407975

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

organonitrogen compound metabolic process [inference]

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

heme metabolic process [inference]

heme biosynthetic process

heme a metabolic process [inference]

heme A biosynthetic process

heme B metabolic process [inference]

heme B biosynthetic process

heme O metabolic process [inference]

heme O biosynthetic process

protoporphyrinogen IX metabolic process [inference]

protoporphyrinogen IX biosynthetic process

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

organonitrogen compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

heterocycle biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

aromatic compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

organic substance biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

organonitrogen compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

pigment metabolic process [inference]

heme metabolic process [inference]

heme biosynthetic process

heme a metabolic process [inference]

heme A biosynthetic process

heme B metabolic process [inference]

heme B biosynthetic process

heme O metabolic process [inference]

heme O biosynthetic process

pigment biosynthetic process [inference]

heme biosynthetic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

aromatic compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

heme metabolic process [inference]

heme biosynthetic process

heme a metabolic process [inference]

heme A biosynthetic process

heme B metabolic process [inference]

heme B biosynthetic process

heme O metabolic process [inference]

heme O biosynthetic process

protoporphyrinogen IX metabolic process [inference]

protoporphyrinogen IX biosynthetic process

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

cellular biosynthetic process [inference]

heterocycle biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

aromatic compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

heme metabolic process [inference]

heme biosynthetic process

heme a metabolic process [inference]

heme A biosynthetic process

heme B metabolic process [inference]

heme B biosynthetic process

heme O metabolic process [inference]

heme O biosynthetic process

protoporphyrinogen IX metabolic process [inference]

protoporphyrinogen IX biosynthetic process

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

organic substance metabolic process [inference]

organic cyclic compound metabolic process [inference]

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

heme metabolic process [inference]

heme biosynthetic process

heme a metabolic process [inference]

heme A biosynthetic process

heme B metabolic process [inference]

heme B biosynthetic process

heme O metabolic process [inference]

heme O biosynthetic process

protoporphyrinogen IX metabolic process [inference]

protoporphyrinogen IX biosynthetic process

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

organic cyclic compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

organonitrogen compound metabolic process [inference]

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

heme metabolic process [inference]

heme biosynthetic process

heme a metabolic process [inference]

heme A biosynthetic process

heme B metabolic process [inference]

heme B biosynthetic process

heme O metabolic process [inference]

heme O biosynthetic process

protoporphyrinogen IX metabolic process [inference]

protoporphyrinogen IX biosynthetic process

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

organonitrogen compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

organic substance biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

organonitrogen compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

aromatic compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

heme metabolic process [inference]

heme biosynthetic process

heme a metabolic process [inference]

heme A biosynthetic process

heme B metabolic process [inference]

heme B biosynthetic process

heme O metabolic process [inference]

heme O biosynthetic process

protoporphyrinogen IX metabolic process [inference]

protoporphyrinogen IX biosynthetic process

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

cellular biosynthetic process [inference]

heterocycle biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

aromatic compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

heme metabolic process [inference]

heme biosynthetic process

heme a metabolic process [inference]

heme A biosynthetic process

heme B metabolic process [inference]

heme B biosynthetic process

heme O metabolic process [inference]

heme O biosynthetic process

protoporphyrinogen IX metabolic process [inference]

protoporphyrinogen IX biosynthetic process

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heme biosynthetic process

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

establishment or maintenance of transmembrane electrochemical gradient

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

monoatomic ion transmembrane transport [inference]

establishment or maintenance of transmembrane electrochemical gradient

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

establishment or maintenance of transmembrane electrochemical gradient

Displaying entries **6 - 9** of 9 in total

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GO Term	Evidence Code	PMID
mitochondrial intermembrane space	IDA	8407975
cytosol	ISO
cytosol	IEA
membrane	IMP	20080761

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

organelle envelope lumen [inference]

mitochondrial intermembrane space

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
coproporphyrinogen oxidase activity	ISO
coproporphyrinogen oxidase activity	IDA	7607249 8407975
coproporphyrinogen oxidase activity	IBA
structural constituent of eye lens	IMP	12470976
P-type sodium:potassium-exchanging transporter activity	TAS	12470976

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the CH-CH group of donors [inference]

oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor [inference]

coproporphyrinogen oxidase activity

structural molecule activity [inference]

structural constituent of eye lens

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

sodium ion transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

active monoatomic ion transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

sodium ion transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type transmembrane transporter activity [inference]

P-type ion transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

active monoatomic ion transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

salt transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

sodium ion transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

binding [inference]

protein binding [inference]

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type transmembrane transporter activity [inference]

P-type ion transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

coproporphyrinogen_III_oxidase

Functional Category

H: Coenzyme transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
coproporphyrinogen oxidase activity
heme biosynthetic process
oxidoreductase activity
porphyrin-containing compound biosynthetic process
protoporphyrinogen IX biosynthetic process

Displaying **all 3** entries
InterPro
Coproporphyrinogen III oxidase, aerobic
Coproporphyrinogen III oxidase, conserved site
Oxygen-dependent coproporphyrinogen III oxidase superfamily

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:13269	hereditary coproporphyria	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements