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MIRAGE
membrane bound glycerophospholipid O-acyltransferase 2

Summary
Gene Symbol
  • MBOAT2
Aliases
  • FLJ14415
  • FLJ90298
  • LPLAT13
  • Lysophospholipid acyltransferase 2
  • lysophospholipid acyltransferase 13
Organism
Homo sapiens (human)
NCBI Gene
129642
HGNC
25193
KEGG Gene ID
hsa:129642
PubChem
129642
Alliance of Genome Resources
JoGo
MBOAT2
TogoVar
MBOAT2
Annotation
Keyword
  • Acyltransferase
  • Endoplasmic reticulum
  • Phospholipid biosynthesis
  • Proteomics identification
  • Reference proteome
  • Transmembrane helix
Proteins
Displaying all 3 entries
UniProt Protein Name
Q6ZWT7
  • 1-acylglycerophosphate O-acyltransferase MBOAT2
  • 1-acylglycerophosphocholine O-acyltransferase MBOAT2
  • 1-acylglycerophosphoethanolamine MBOAT2 O-acyltransferase
  • Lysophosphatidic acid acyltransferase
  • Lysophosphatidylcholine acyltransferase
  • Lysophosphatidylcholine acyltransferase 4
  • Lysophosphatidylethanolamine acyltransferase
  • Lysophospholipid acyltransferase 2
  • Membrane-bound O-acyltransferase domain-containing protein 2
B7Z3I3
B0AZU0
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 10 in total
GO Term Evidence Code PMID
phospholipid biosynthetic process
lipid modification
regulation of chondrocyte differentiation
phosphatidylserine acyl-chain remodeling
phosphatidylcholine acyl-chain remodeling
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
Human Protein Atlas
ENSG00000143797

soft tissue soft tissue blood blood blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node kidney kidney adrenal gland adrenal gland breast breast duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland nasopharynx nasopharynx tongue tonsil tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder ductus deferens ductus deferens seminal vesicle seminal vesicle seminal vesicle seminal vesicle testis testis epididymis epididymis brain smooth muscle urinary bladder prostate bone marrow skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus cartilage sole of foot sole of foot soft tissue blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lactating breast lactating breast kidney kidney adrenal gland adrenal gland duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland salivary gland salivary gland salivary gland salivary gland salivary gland nasopharynx tongue tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder brain skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus smooth muscle urinary bladder vagina ovary ovary fallopian tube fallopian tube endometrium placenta cervix cervix bone marrow cartilage sole of foot sole of foot olfactory region cerebral cortex cerebellum medulla pons midbrain pituitary gland hypothalamus amygdala thalamus choroid plexus choroid plexus corpus callosum basal ganglia substantia nigra dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe caudate hippocampus retina retina

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas
KEGG BRITE Database
Orthology
K13517
Name
lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-]
References
Rhea

RHEA:19709

a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA
CoA + a 1,2-diacyl-sn-glycero-3-phosphate
Enzyme
PMID

RHEA:12937

a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA
CoA + a 1,2-diacyl-sn-glycero-3-phosphocholine
Enzyme
PMID

RHEA:32995

an acyl-CoA + a 1-acyl-sn-glycero-3-phosphoethanolamine
CoA + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine
Enzyme
PMID
LIPID MAPS Gene / Proteome Database
LMPD ID
LMP012365
Gene Name
membrane bound O-acyltransferase domain containing 2
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026