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colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)

Summary

Gene Symbol

Csf2rb2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

12984

PubChem

12984

Alliance of Genome Resources

MGI:1339760

Annotation

Keyword

3D-structure
Disulfide bond
Glycoprotein
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q3U1Z1
A0A2R8VHE8
P26954	Colony-stimulating factor 2 receptor subunit beta-2 Interleukin-3 receptor class II beta chain

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
receptor signaling pathway via JAK-STAT	ISO
immunoglobulin mediated immune response	IBA
cytokine-mediated signaling pathway	IBA
cytokine-mediated signaling pathway	IEA
interleukin-5-mediated signaling pathway	ISO

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

leukocyte mediated immunity [inference]

lymphocyte mediated immunity [inference]

B cell mediated immunity [inference]

immunoglobulin mediated immune response

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

B cell mediated immunity [inference]

immunoglobulin mediated immune response

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

receptor signaling pathway via STAT [inference]

receptor signaling pathway via JAK-STAT

response to stimulus [inference]

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

B cell mediated immunity [inference]

immunoglobulin mediated immune response

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

receptor signaling pathway via STAT [inference]

receptor signaling pathway via JAK-STAT

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation

regulation of leukocyte proliferation [inference]

positive regulation of leukocyte proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane	ISO
plasma membrane	IDA	1695379
external side of plasma membrane	IBA
granulocyte macrophage colony-stimulating factor receptor complex	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

granulocyte macrophage colony-stimulating factor receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

granulocyte macrophage colony-stimulating factor receptor complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

side of membrane [inference]

external side of plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cytokine receptor activity	IBA
cytokine receptor activity	IEA
coreceptor activity	ISO

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity

coreceptor activity

immune receptor activity [inference]

cytokine receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

cytokine receptor common subunit

Functional Category

E: Amino acid transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
InterPro
Fibronectin type III superfamily
Fibronectin type III
Immunoglobulin-like fold

Ortholog

Displaying entries **1 - 10** of 43 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	1439	Xenbase:XB-GENE-483530	HUMAN60339
Xenopus tropicalis	12983	Xenbase:XB-GENE-483530
Xenopus tropicalis	12984	Xenbase:XB-GENE-483530
Rattus norvegicus	171081		RATNO37674
Pan troglodytes	458802		PANTR26477
Canis lupus familiaris	481276		CANLF01655
Bos taurus	528530		BOVIN29957
Macaca mulatta	697508		MACMU00733
Equus caballus	100054613		HORSE26295
Sus scrofa	100153254		PIGXX25158