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neurocan

Summary

Gene Symbol

Ncan

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

13004

PubChem

13004

Alliance of Genome Resources

MGI:104694

Annotation

Keyword

Calcium
Cell adhesion
Disulfide bond
EGF-like domain
Hyaluronic acid
Immunoglobulin domain
Lectin
Proteoglycan
Proteomics identification
Reference proteome
Repeat
Secreted
Signal
Sushi

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A0R4IZX5
P55066	Chondroitin sulfate proteoglycan 3

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
skeletal system development	IBA
cell adhesion	IEA
central nervous system development	IBA
modulation of chemical synaptic transmission	IDA	11486035
modulation of chemical synaptic transmission	IMP	11486035

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

developmental process [inference]

anatomical structure development [inference]

system development [inference]

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
extracellular region	IEA
extracellular space	IBA
plasma membrane	TAS
extracellular matrix
synapse	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell junction [inference]

synapse

external encapsulating structure [inference]

extracellular matrix

collagen-containing extracellular matrix [inference]

perisynaptic extracellular matrix

perineuronal net

Displaying **all 3** entries
GO Term	Evidence Code	PMID
calcium ion binding	IEA
hyaluronic acid binding	IEA
carbohydrate binding	IEA

GO Hierarchy

molecular function

binding [inference]

carbohydrate binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

hyaluronic acid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

neurocan core protein

Functional Category

O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
calcium ion binding
central nervous system development
hyaluronic acid binding
positive regulation of neuroblast proliferation
skeletal system development

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InterPro
C-type lectin fold
C-type lectin, conserved site
C-type lectin-like/link domain superfamily
C-type lectin-like
EGF-like calcium-binding domain
EGF-like calcium-binding, conserved site
EGF-like domain
EGF-type aspartate/asparagine hydroxylation site
Immunoglobulin V-set domain
Immunoglobulin subtype

Ortholog

Displaying entries **11 - 20** of 62 in total

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Species	Gene ID	Orthologous MAtrix
Pongo abelii	100460345	PONAB14055
Ailuropoda melanoleuca	100482310	AILME19313
Nomascus leucogenys	100585998	NOMLE01937
Oreochromis niloticus	100695628	ORENI44503
Cricetulus griseus	100766384	CRIGR05615
Otolemur garnettii	100940538	OTOGA06334
Pan paniscus	100995880	PANPA19970
Papio anubis	101005836	PAPAN23750
Saimiri boliviensis boliviensis	101038108	SAIBB36346
Takifugu rubripes	101069781	TAKRU27697