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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
cathepsin B
Summary
- Gene Symbol
-
- Ctsb
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Cell membrane
- Disulfide bond
- Glycoprotein
- Lysosome
- Reference proteome
- Secreted
- Signal
- Thiol protease
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| P10605 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of catalytic activity | ||
| proteolysis | ||
| cellular response to thyroid hormone stimulus | ||
| collagen catabolic process | ||
| protein catabolic process |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| sarcolemma | ||
| apical plasma membrane | ||
| collagen-containing extracellular matrix | ||
| peptidase inhibitor complex |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| cysteine-type endopeptidase activity | ||
| protein-containing complex binding | ||
| identical protein binding | ||
| endopeptidase activity | ||
| collagen binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- cathepsin B
- Functional Category
-
- E: Amino acid transport and metabolism
- F: Nucleotide transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
| Gene Ontology |
|---|
| cysteine-type endopeptidase activity |
| hydrolase activity |
| proteolysis involved in protein catabolic process |
| proteolysis |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080322 | polycystic kidney disease | |
| DOID:0080998 | acute necrotizing pancreatitis | |
| DOID:10754 | otitis media | |
| DOID:10941 | intracranial aneurysm | |
| DOID:11054 | urinary bladder cancer | |
| DOID:12842 | Guillain-Barre syndrome | |
| DOID:14219 | renal tubular acidosis | |
| DOID:1612 | breast cancer | |
| DOID:2316 | brain ischemia | |
| DOID:2377 | multiple sclerosis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 1508 | HGNC:2527 | HUMAN92520 | ||
| 32341 | FB:FBgn0030521 | |||
| 64529 | 10116_1:0046ba | RGD:621509 | RATNO10421 | |
| 178611 | WB:WBGene00021072 | |||
| 178612 | WB:WBGene00000785 | |||
| 179053 | WB:WBGene00000784 | |||
| 179637 | WB:WBGene00000781 | |||
| 179645 | WB:WBGene00010204 | |||
| 179815 | WB:WBGene00009347 | |||
| 180033 | WB:WBGene00000783 |
