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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
cathepsin B
Summary
- Gene Symbol
-
- Ctsb
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Cell membrane
- Disulfide bond
- Glycoprotein
- Lysosome
- Reference proteome
- Secreted
- Signal
- Thiol protease
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| P10605 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| neuron apoptotic process |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| cell surface | ||
| melanosome | ||
| mitochondrion | ||
| lysosome |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| cysteine-type endopeptidase activity | ||
| protein-containing complex binding | ||
| identical protein binding | ||
| endopeptidase activity | ||
| collagen binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- cathepsin B
- Functional Category
-
- E: Amino acid transport and metabolism
- F: Nucleotide transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
| Gene Ontology |
|---|
| cysteine-type endopeptidase activity |
| hydrolase activity |
| proteolysis involved in protein catabolic process |
| proteolysis |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080322 | polycystic kidney disease | |
| DOID:0080998 | acute necrotizing pancreatitis | |
| DOID:10754 | otitis media | |
| DOID:10941 | intracranial aneurysm | |
| DOID:11054 | urinary bladder cancer | |
| DOID:12842 | Guillain-Barre syndrome | |
| DOID:14219 | renal tubular acidosis | |
| DOID:1612 | breast cancer | |
| DOID:2316 | brain ischemia | |
| DOID:2377 | multiple sclerosis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 119799760 | 1047088_0:004812 | |||
| 121456455 | 111838_0:000539 | |||
| 122125257 | 105255_0:003ab1 | |||
| 122217689 | PANLE26449 | |||
| 123793572 | URSAM10352 | |||
| 124102864 | 9995_0:00238d | |||
| 124982517 | 30640_0:001844 | |||
| 125339475 | 214514_0:004352 | |||
| 125392471 | 447135_0:0043d3 | |||
| 126507571 | 100897_0:0024bf |
