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Standards Ontologies Notations
Guidelines
MIRAGE
cytochrome P450, family 2, subfamily a, polypeptide 4

Summary
Gene Symbol
  • Cyp2a4
Organism
Mus musculus (house mouse)
NCBI Gene
13086
PubChem
13086
Alliance of Genome Resources
Annotation
Keyword
  • Acetylation
  • Heme
  • Membrane
  • Microsome
  • Monooxygenase
  • Phosphoprotein
  • Reference proteome
Proteins
Displaying 1 entry
UniProt Protein Name
P15392
  • CYPIIA4
  • Cytochrome P450-15-alpha
  • Cytochrome P450-IIA3.1
  • Testosterone 15-alpha-hydroxylase
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 4 entries
GO Term Evidence Code PMID
xenobiotic metabolic process
coumarin metabolic process
epoxygenase P450 pathway
response to stilbenoid
GO Hierarchy
Displaying entries 1 - 5 of 10 in total
GO Term Evidence Code PMID
iron ion binding
coumarin 7-hydroxylase activity
arachidonic acid epoxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
CYTOCHROME P450
Functional Category
  • I: Lipid transport and metabolism
  • Q: Secondary metabolites biosynthesis, transport and catabolism
  • T: Signal transduction mechanisms
Displaying all 6 entries
Gene Ontology
heme binding
iron ion binding
metal ion binding
monooxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity
Displaying all 4 entries
InterPro
Cytochrome P450 superfamily
Cytochrome P450, E-class, group I
Cytochrome P450, conserved site
Cytochrome P450
Ortholog
Displaying entries 1 - 10 of 78 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
1553 HUMAN43711
1555 Xenbase:XB-GENE-5892286
1557 ZFIN:ZDB-GENE-050522-490
1558 ZFIN:ZDB-GENE-050522-490
1559 ZFIN:ZDB-GENE-050522-490
1562 ZFIN:ZDB-GENE-050522-490
1564 WB:WBGene00019565
1571 ZFIN:ZDB-GENE-050522-490
1573 WB:WBGene00019565
13085 Xenbase:XB-GENE-5892286
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025