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damage specific DNA binding protein 1

Summary

Gene Symbol

Ddb1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

13194

PubChem

13194

Alliance of Genome Resources

MGI:1202384

Gene Ontology (GO)

Displaying entries **1 - 5** of 46 in total

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GO Term	Evidence Code	PMID
DNA repair	IBA
ubiquitin-dependent protein catabolic process	ISO
ubiquitin-dependent protein catabolic process	IMP	26431207
apoptotic process	IMP	24357321
cellular response to DNA damage stimulus	ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

UV-damage excision repair

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

UV-damage excision repair

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

UV-damage excision repair

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

UV-damage excision repair

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

UV-damage excision repair

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

UV-damage excision repair

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

UV-damage excision repair

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

spindle organization [inference]

meiotic spindle organization [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis

spindle assembly [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

cell death [inference]

programmed cell death [inference]

apoptotic process

programmed cell death involved in cell development [inference]

ectopic germ cell programmed cell death

cell cycle process [inference]

spindle organization [inference]

meiotic spindle organization [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis

spindle assembly [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis

meiotic cell cycle process [inference]

meiotic spindle organization [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis

cellular process involved in reproduction in multicellular organism [inference]

spindle assembly involved in female meiosis

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

UV-damage excision repair

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

UV-damage excision repair

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

UV-damage excision repair

cellular developmental process [inference]

programmed cell death involved in cell development [inference]

ectopic germ cell programmed cell death

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

DNA repair

UV-damage excision repair

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

UV-damage excision repair

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

spindle organization [inference]

meiotic spindle organization [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis

spindle assembly [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

spindle assembly [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis

cellular component assembly [inference]

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

spindle assembly [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling [inference]

epigenetic regulation of gene expression [inference]

post-fertilization epigenetic regulation of gene expression [inference]

epigenetic programming in the zygotic pronuclei

viral process [inference]

viral release from host cell

reproductive process [inference]

developmental process involved in reproduction [inference]

ectopic germ cell programmed cell death

cellular process involved in reproduction in multicellular organism [inference]

spindle assembly involved in female meiosis

meiotic cell cycle process [inference]

meiotic spindle organization [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis

developmental process [inference]

developmental process involved in reproduction [inference]

ectopic germ cell programmed cell death

cellular developmental process [inference]

programmed cell death involved in cell development [inference]

ectopic germ cell programmed cell death

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

exit from host cell [inference]

viral release from host cell

biological process involved in interaction with symbiont

rhythmic process

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

DNA repair

UV-damage excision repair

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

response to UV [inference]

cellular response to UV

UV-damage excision repair

cellular response to light stimulus [inference]

cellular response to UV

UV-damage excision repair

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

UV-damage excision repair

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

UV-damage excision repair

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

DNA repair

UV-damage excision repair

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

UV-damage excision repair

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of gluconeogenesis

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

epigenetic regulation of gene expression [inference]

post-fertilization epigenetic regulation of gene expression [inference]

epigenetic programming in the zygotic pronuclei

positive regulation of cellular biosynthetic process [inference]

positive regulation of gluconeogenesis

regulation of carbohydrate biosynthetic process [inference]

regulation of gluconeogenesis [inference]

positive regulation of gluconeogenesis

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of gluconeogenesis

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of gluconeogenesis

positive regulation of carbohydrate metabolic process [inference]

positive regulation of glucose metabolic process [inference]

positive regulation of gluconeogenesis

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of small molecule metabolic process [inference]

positive regulation of glucose metabolic process [inference]

positive regulation of gluconeogenesis

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of gluconeogenesis

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

epigenetic regulation of gene expression [inference]

post-fertilization epigenetic regulation of gene expression [inference]

epigenetic programming in the zygotic pronuclei

positive regulation of cellular biosynthetic process [inference]

positive regulation of gluconeogenesis

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

epigenetic regulation of gene expression [inference]

post-fertilization epigenetic regulation of gene expression [inference]

epigenetic programming in the zygotic pronuclei

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of small molecule metabolic process [inference]

regulation of glucose metabolic process [inference]

regulation of gluconeogenesis [inference]

positive regulation of gluconeogenesis

positive regulation of glucose metabolic process [inference]

positive regulation of gluconeogenesis

positive regulation of small molecule metabolic process [inference]

positive regulation of glucose metabolic process [inference]

positive regulation of gluconeogenesis

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of glucose metabolic process [inference]

regulation of gluconeogenesis [inference]

positive regulation of gluconeogenesis

positive regulation of glucose metabolic process [inference]

positive regulation of gluconeogenesis

regulation of carbohydrate biosynthetic process [inference]

regulation of gluconeogenesis [inference]

positive regulation of gluconeogenesis

positive regulation of carbohydrate metabolic process [inference]

positive regulation of glucose metabolic process [inference]

positive regulation of gluconeogenesis

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of circadian rhythm

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of gluconeogenesis

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of gluconeogenesis

positive regulation of carbohydrate metabolic process [inference]

positive regulation of glucose metabolic process [inference]

positive regulation of gluconeogenesis

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of small molecule metabolic process [inference]

positive regulation of glucose metabolic process [inference]

positive regulation of gluconeogenesis

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of gluconeogenesis

positive regulation of viral process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of viral process [inference]

regulation by virus of viral protein levels in host cell [inference]

positive regulation by virus of viral protein levels in host cell

positive regulation of viral process [inference]

regulation of viral life cycle [inference]

regulation of viral genome replication [inference]

positive regulation of viral genome replication

regulation of developmental process [inference]

negative regulation of developmental process

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of gluconeogenesis

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

epigenetic regulation of gene expression [inference]

post-fertilization epigenetic regulation of gene expression [inference]

epigenetic programming in the zygotic pronuclei

positive regulation of cellular biosynthetic process [inference]

positive regulation of gluconeogenesis

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of gluconeogenesis

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

regulation of mitotic cell cycle phase transition

regulation of cell cycle process [inference]

regulation of cell cycle phase transition [inference]

regulation of mitotic cell cycle phase transition

regulation of reproductive process [inference]

negative regulation of reproductive process

regulation of biological quality [inference]

regulation by virus of viral protein levels in host cell [inference]

positive regulation by virus of viral protein levels in host cell

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GO Term	Evidence Code	PMID
nucleus	ISS
nucleus	ISO
nucleus	NAS	22118460
nucleus	IBA
nucleoplasm	ISO

GO Hierarchy

cellular component

protein-containing complex

intracellular protein-containing complex [inference]

ubiquitin ligase complex [inference]

cullin-RING ubiquitin ligase complex [inference]

Cul4-RING E3 ubiquitin ligase complex

catalytic complex [inference]

transferase complex [inference]

ubiquitin ligase complex [inference]

cullin-RING ubiquitin ligase complex [inference]

Cul4-RING E3 ubiquitin ligase complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

nucleolus

site of DNA damage [inference]

site of double-strand break

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
damaged DNA binding	ISO
damaged DNA binding	IEA
protein binding	IPI	24855944 26323038 27123980 30111536 30442713
protein-macromolecule adaptor activity	ISO
protein-containing complex binding	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding

protein domain specific binding [inference]

WD40-repeat domain binding

cullin family protein binding

protein-containing complex binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding [inference]

damaged DNA binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity

ubiquitin ligase complex scaffold activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

binding protein

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
DNA repair
proteasome-mediated ubiquitin-dependent protein catabolic process

Displaying **all 3** entries
InterPro
Cleavage/polyadenylation specificity factor, A subunit, C-terminal
Cleavage/polyadenylation specificity factor, A subunit, N-terminal
WD40/YVTN repeat-like-containing domain superfamily

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

OrthoDB (Group)

International Collaboration

Acknowledgements