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phosphogluconate dehydrogenase

Summary

Gene Symbol

PGD

Organism

Mustela nigripes (black-footed ferret)

External Links

NCBI Gene: 132001103
KEGG Gene ID: mnp:132001103
PubChem: 132001103

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
pentose-phosphate shunt, oxidative branch	IEA	30032202
pentose-phosphate shunt	IEA	22301074
D-gluconate catabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

oligosaccharide catabolic process [inference]

D-gluconate catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

aldonic acid metabolic process [inference]

D-gluconate metabolic process [inference]

D-gluconate catabolic process

aldonic acid catabolic process [inference]

D-gluconate catabolic process

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

generation of precursor metabolites and energy [inference]

NADPH regeneration [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

glucose 6-phosphate metabolic process [inference]

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

glucose 6-phosphate metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

primary metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process [inference]

oligosaccharide catabolic process [inference]

D-gluconate catabolic process

D-gluconate metabolic process [inference]

D-gluconate catabolic process

carbohydrate catabolic process [inference]

oligosaccharide catabolic process [inference]

D-gluconate catabolic process

aldonic acid metabolic process [inference]

D-gluconate metabolic process [inference]

D-gluconate catabolic process

aldonic acid catabolic process [inference]

D-gluconate catabolic process

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

aldonic acid metabolic process [inference]

D-gluconate metabolic process [inference]

D-gluconate catabolic process

aldonic acid catabolic process [inference]

D-gluconate catabolic process

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process [inference]

oligosaccharide catabolic process [inference]

D-gluconate catabolic process

D-gluconate metabolic process [inference]

D-gluconate catabolic process

carbohydrate catabolic process [inference]

oligosaccharide catabolic process [inference]

D-gluconate catabolic process

aldonic acid metabolic process [inference]

D-gluconate metabolic process [inference]

D-gluconate catabolic process

aldonic acid catabolic process [inference]

D-gluconate catabolic process

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

aldonic acid metabolic process [inference]

D-gluconate metabolic process [inference]

D-gluconate catabolic process

aldonic acid catabolic process [inference]

D-gluconate catabolic process

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

glucose 6-phosphate metabolic process [inference]

carbohydrate derivative metabolic process [inference]

glucose 6-phosphate metabolic process [inference]

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

oligosaccharide catabolic process [inference]

D-gluconate catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

aldonic acid metabolic process [inference]

D-gluconate metabolic process [inference]

D-gluconate catabolic process

aldonic acid catabolic process [inference]

D-gluconate catabolic process

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

generation of precursor metabolites and energy [inference]

NADPH regeneration [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

glucose 6-phosphate metabolic process [inference]

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

glucose 6-phosphate metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

Displaying 1 entry
GO Term	Evidence Code	PMID
cytosol	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying **all 2** entries
GO Term	Evidence Code	PMID
NADP binding	IEA	22301074 30032202
phosphogluconate dehydrogenase (decarboxylating) activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

phosphogluconate dehydrogenase (decarboxylating) activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Carnivora

Group Name

6-phosphogluconate dehydrogenase

Functional Category

G: Carbohydrate transport and metabolism
I: Lipid transport and metabolism
J: Translation, ribosomal structure and biogenesis
M: Cell wall/membrane/envelope biogenesis

Displaying **all 8** entries
Gene Ontology
D-gluconate catabolic process
D-gluconate metabolic process
NADP binding
oxidoreductase activity
pentose-phosphate shunt, oxidative branch
pentose-phosphate shunt
phosphogluconate 2-dehydrogenase activity
phosphogluconate dehydrogenase (decarboxylating) activity

Displaying **all 8** entries
InterPro
6-phosphogluconate dehydrogenase, C-terminal
6-phosphogluconate dehydrogenase, NADP-binding
6-phosphogluconate dehydrogenase, decarboxylating
6-phosphogluconate dehydrogenase, domain 2
6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
6-phosphogluconate dehydrogenase
6-phosphogluconate-binding site
NAD(P)-binding domain superfamily

KEGG BRITE Database

Orthology

K00033

Name

6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]

References

Ortholog

Displaying entries **31 - 40** of 44 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Panthera leo	122228624	9689_0:002505
Prionailurus bengalensis	122482074	37029_0:000cc5
Neogale vison	122899436	452646_0:000824
Leopardus geoffroyi	123599802	46844_0:000cb1
Ursus americanus	123779087	9643_0:0042b9
Mirounga angustirostris	123860450	9716_0:00333a
Meles meles	123937533	9662_0:00063d
Lynx rufus	124514809	61384_0:001c3f
Lutra lutra	125096812	9657_0:0010f2
Prionailurus viverrinus	125171943	61388_0:002186

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Last updated: December 9, 2024