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MIRAGE
discs large MAGUK scaffold protein 4

Summary
Gene Symbol
  • Dlg4
Organism
Mus musculus (house mouse)
NCBI Gene
13385
PubChem
13385
Alliance of Genome Resources
Annotation
Keyword
  • Alternative splicing
  • Cell membrane
  • Cell projection
  • Cytoplasm
  • Palmitate
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Repeat
  • SH3 domain
  • Signal
  • Synapse
  • Ubl conjugation
Proteins
Displaying all 3 entries
UniProt Protein Name
A0A338P6E5
  • Postsynaptic density protein 95
  • Synapse-associated protein 90
Q62108
  • Postsynaptic density protein 95
  • Synapse-associated protein 90
A0A338P6I6
  • Postsynaptic density protein 95
  • Synapse-associated protein 90
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 52 in total
GO Term Evidence Code PMID
negative regulation of receptor internalization
negative regulation of receptor internalization
positive regulation of cytosolic calcium ion concentration
positive regulation of cytosolic calcium ion concentration
chemical synaptic transmission
GO Hierarchy
Displaying entries 6 - 10 of 51 in total
GO Term Evidence Code PMID
cell-cell junction
synaptic vesicle
voltage-gated potassium channel complex
voltage-gated potassium channel complex
postsynaptic density
GO Hierarchy
Displaying entries 1 - 5 of 34 in total
GO Term Evidence Code PMID
signaling receptor binding
frizzled binding
structural molecule activity
protein binding
protein binding
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
Disks large
Functional Category
  • E: Amino acid transport and metabolism
  • J: Translation, ribosomal structure and biogenesis
  • T: Signal transduction mechanisms
Displaying all 5 entries
Gene Ontology
chemical synaptic transmission
establishment or maintenance of epithelial cell apical/basal polarity
kinase binding
receptor clustering
receptor localization to synapse
Displaying all 8 entries
InterPro
Guanylate kinase, conserved site
Guanylate kinase-like domain
Guanylate kinase/L-type calcium channel beta subunit
P-loop containing nucleoside triphosphate hydrolase
PDZ domain
PDZ superfamily
SH3 domain
SH3-like domain superfamily
Disease
Disease Ontology
Displaying all 2 entries
DO ID Disease Name Source
DOID:0060041 autism spectrum disorder
DOID:1928 Williams-Beuren syndrome
Ortholog
Displaying entries 21 - 30 of 65 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
101018290 PAPAN14032
101027754 SAIBB15343
101093902 FELCA31329
101145671 GORGO13243
101572179 OCTDE17021
101596670 JACJA21191
101677223 MUSPF10170
101708587 HETGA02900
101967686 ICTTR16554
102028518 CHILA16237
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025