GlyCosmos Portal

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GO Term	Evidence Code	PMID
protein binding	IPI	28514442 32296183 33961781
carboxylic ester hydrolase activity	IEA
acetyl-CoA hydrolase activity	IBA ISS
identical protein binding	IPI	32296183
lipid binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

thiolester hydrolase activity [inference]

CoA hydrolase activity [inference]

acetyl-CoA hydrolase activity

carboxylic ester hydrolase activity

binding [inference]

protein binding

identical protein binding

lipid binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

thioesterase

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 4** entries
Gene Ontology
acyl-CoA metabolic process
fatty acid metabolic process
lipid binding
thiolester hydrolase activity

Displaying **all 6** entries
InterPro
Cytosolic acyl coenzyme A thioester hydrolase
HotDog domain superfamily
Hotdog acyl-CoA thioesterase (ACOT)-type domain
START domain
START-like domain superfamily
Thioesterase domain

Rhea

RHEA:20289

H₂O + acetyl-CoA

H⁺ + acetate + CoA

Enzyme

3.1.2.1

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:3571	liver cancer	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP000094
Gene Name: acyl-CoA thioesterase 12

Ortholog

Displaying entries **21 - 30** of 57 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Pan paniscus	100970341	9597_0:001722	PANPA31637
Papio anubis	101004670		PAPAN31220
Saimiri boliviensis boliviensis	101041377		SAIBB01744
Felis catus	101091423		FELCA02449
Ovis aries	101118188		SHEEP17022
Gorilla gorilla gorilla	101152146	9595_0:001978	GORGO32595
Octodon degus	101579359		OCTDE18795
Ficedula albicollis	101810335		FICAL12398
Chrysemys picta bellii	101931735		CHRPI03335
Ictidomys tridecemlineatus	101955717		ICTTR10003

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements