GlyCosmos Portal

Submissions

dopamine receptor D5

Summary

Gene Symbol

Drd5

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

13492

PubChem

13492

Alliance of Genome Resources

MGI:94927

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Palmitate
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B2RQS5	D(5) dopamine receptor Dopamine D5 receptor
Q8BLD9	D(5) dopamine receptor Dopamine D5 receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 29 in total

1

2

3

4

5

6

Next ›

Last »
GO Term	Evidence Code	PMID
synaptic transmission, dopaminergic	IEA
response to amphetamine	IGI	11823893
regulation of systemic arterial blood pressure by vasopressin	IGI	12486173
norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure	IMP	12486173
adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

reactive oxygen species metabolic process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, dopaminergic

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

adrenergic receptor signaling pathway [inference]

adenylate cyclase-activating adrenergic receptor signaling pathway

dopamine receptor signaling pathway

adenylate cyclase-activating dopamine receptor signaling pathway

cellular metabolic process [inference]

reactive oxygen species metabolic process

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to catecholamine stimulus

cellular response to organonitrogen compound [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus

cellular response to oxygen-containing compound [inference]

cellular response to catecholamine stimulus

reproductive process [inference]

reproductive behavior [inference]

mating behavior

female mating behavior [inference]

regulation of female receptivity

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

vasoconstriction [inference]

norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure

nervous system process [inference]

transmission of nerve impulse

cognition [inference]

learning or memory [inference]

learning [inference]

associative learning

visual learning

nonassociative learning [inference]

sensitization

endocrine process [inference]

regulation of systemic arterial blood pressure by hormone [inference]

regulation of systemic arterial blood pressure by vasopressin

behavior [inference]

learning or memory [inference]

learning [inference]

associative learning

visual learning

nonassociative learning [inference]

sensitization

visual behavior [inference]

visual learning

reproductive behavior [inference]

mating behavior

female mating behavior [inference]

regulation of female receptivity

response to stimulus [inference]

response to stress [inference]

response to wounding [inference]

wound healing

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

visual behavior [inference]

visual learning

response to endogenous stimulus [inference]

cellular response to endogenous stimulus [inference]

cellular response to organonitrogen compound [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

response to amine [inference]

response to amphetamine

response to alkaloid [inference]

response to cocaine

cellular response to organonitrogen compound [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus

response to monoamine [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus

response to catecholamine [inference]

cellular response to catecholamine stimulus

response to organic cyclic compound [inference]

response to cocaine

cellular response to organic cyclic compound [inference]

cellular response to catecholamine stimulus

response to catecholamine [inference]

cellular response to catecholamine stimulus

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to catecholamine stimulus

cellular response to organonitrogen compound [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to catecholamine stimulus

cellular response to organonitrogen compound [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus

cellular response to oxygen-containing compound [inference]

cellular response to catecholamine stimulus

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to amine [inference]

response to amphetamine

response to alkaloid [inference]

response to cocaine

cellular response to organonitrogen compound [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus

response to monoamine [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus

response to catecholamine [inference]

cellular response to catecholamine stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus

response to oxygen-containing compound [inference]

response to cocaine

response to catecholamine [inference]

cellular response to catecholamine stimulus

cellular response to oxygen-containing compound [inference]

cellular response to catecholamine stimulus

response to salt [inference]

response to cocaine

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to catecholamine stimulus

cellular response to organonitrogen compound [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus

cellular response to oxygen-containing compound [inference]

cellular response to catecholamine stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

negative regulation of signaling [inference]

negative regulation of synaptic transmission [inference]

long-term synaptic depression

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity [inference]

long-term synaptic depression

negative regulation of synaptic transmission [inference]

long-term synaptic depression

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, dopaminergic

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

negative regulation of cell migration

negative regulation of cell motility [inference]

negative regulation of cell migration

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of synaptic transmission [inference]

long-term synaptic depression

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of synaptic transmission [inference]

long-term synaptic depression

negative regulation of cell motility [inference]

negative regulation of cell migration

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

adrenergic receptor signaling pathway [inference]

adenylate cyclase-activating adrenergic receptor signaling pathway

dopamine receptor signaling pathway

adenylate cyclase-activating dopamine receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

negative regulation of cell communication [inference]

negative regulation of synaptic transmission [inference]

long-term synaptic depression

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity [inference]

long-term synaptic depression

negative regulation of synaptic transmission [inference]

long-term synaptic depression

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of synaptic transmission [inference]

long-term synaptic depression

negative regulation of cell motility [inference]

negative regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

negative regulation of cell migration

negative regulation of cell motility [inference]

negative regulation of cell migration

regulation of biological quality [inference]

regulation of blood pressure [inference]

regulation of systemic arterial blood pressure [inference]

regulation of systemic arterial blood pressure mediated by a chemical signal [inference]

regulation of systemic arterial blood pressure by hormone [inference]

regulation of systemic arterial blood pressure by vasopressin

negative regulation of blood pressure

regulation of female receptivity

regulation of synaptic plasticity [inference]

long-term synaptic depression

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

vasoconstriction [inference]

norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure

regulation of postsynaptic membrane neurotransmitter receptor levels

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of oxidoreductase activity [inference]

negative regulation of NAD(P)H oxidase activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of oxidoreductase activity [inference]

negative regulation of NAD(P)H oxidase activity

regulation of oxidoreductase activity [inference]

regulation of NAD(P)H oxidase activity [inference]

negative regulation of NAD(P)H oxidase activity

negative regulation of oxidoreductase activity [inference]

negative regulation of NAD(P)H oxidase activity

Displaying entries **1 - 5** of 16 in total

1

2

3

4

Next ›

Last »
GO Term	Evidence Code	PMID
plasma membrane	ISO
plasma membrane	IBA
cilium	ISO	28154160
axon	ISO
dendrite	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

ciliary membrane

plasma membrane region [inference]

cell projection membrane [inference]

synaptic membrane [inference]

postsynaptic specialization membrane [inference]

postsynaptic density membrane

cell junction [inference]

synapse

glutamatergic synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium

non-motile cilium

neuron projection [inference]

neuron spine [inference]

dendritic spine

organelle [inference]

membrane-bounded organelle [inference]

cilium

non-motile cilium

cell body [inference]

neuronal cell body

postsynapse [inference]

dendritic spine

Displaying entries **1 - 5** of 9 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
dopamine neurotransmitter receptor activity, coupled via Gs	IDA	16962565
dopamine neurotransmitter receptor activity, coupled via Gs	IMP	13679419
dopamine neurotransmitter receptor activity, coupled via Gs	IBA
G-protein alpha-subunit binding	ISO
G protein-coupled receptor activity	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

G-protein alpha-subunit binding

ion binding [inference]

cation binding [inference]

dopamine binding

organic cyclic compound binding [inference]

catecholamine binding [inference]

dopamine binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

neurotransmitter receptor activity [inference]

postsynaptic neurotransmitter receptor activity [inference]

dopamine neurotransmitter receptor activity

dopamine neurotransmitter receptor activity, coupled via Gs

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Dopamine receptor

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
adenylate cyclase-activating adrenergic receptor signaling pathway

Displaying **all 2** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Ortholog

Displaying entries **1 - 10** of 63 in total

1

2

3

4

5

…

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	1812	FB:FBgn0011582
Homo sapiens	1816	Xenbase:XB-GENE-992519	HUMAN74897
Drosophila melanogaster	13488	FB:FBgn0011582
Xenopus tropicalis	13492	Xenbase:XB-GENE-992519
Rattus norvegicus	25195	Xenbase:XB-GENE-992519	RATNO08457
Homo sapiens	41726	HGNC:3026
Homo sapiens	180714	HGNC:3026
Pan troglodytes	473340		PANTR33322
Canis lupus familiaris	488824		CANLF12223
Bos taurus	526221		BOVIN31848

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements