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desmocollin 3

Summary

Gene Symbol

Dsc3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

13507

PubChem

13507

Alliance of Genome Resources

MGI:1194993

Annotation

Keyword

Alternative splicing
Calcium
Cell adhesion
Cell junction
Cell membrane
Cleavage on pair of basic residues
Glycoprotein
Metal-binding
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P55850

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
in utero embryonic development	IMP	16418220
homophilic cell adhesion via plasma membrane adhesion molecules	IEA
protein stabilization	ISO
cell-cell adhesion	IBA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

homophilic cell adhesion via plasma membrane adhesion molecules

multicellular organismal process [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

developmental process [inference]

anatomical structure development [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

biological regulation [inference]

regulation of biological quality [inference]

regulation of protein stability [inference]

protein stabilization

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
extracellular region	IDA	17015624
cytoplasm	IDA	16418220
plasma membrane	ISO
plasma membrane	IDA	16418220
cell junction	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell junction

anchoring junction [inference]

cell-cell junction [inference]

desmosome

Displaying **all 3** entries
GO Term	Evidence Code	PMID
calcium ion binding	IBA
calcium ion binding	IEA
gamma-catenin binding	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

gamma-catenin binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

desmocollin-1

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 8** entries
Gene Ontology
adherens junction organization
cadherin binding
calcium ion binding
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
cell-cell adhesion mediated by cadherin
cell-cell junction assembly
homophilic cell adhesion via plasma membrane adhesion molecules
sprouting angiogenesis

Displaying **all 8** entries
InterPro
Cadherin conserved site
Cadherin prodomain
Cadherin, Y-type LIR-motif
Cadherin-like superfamily
Cadherin-like
Cadherin
Catenin binding domain superfamily
Desmosomal cadherin

Ortholog

Displaying entries **41 - 50** of 76 in total

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Species	Gene ID	Orthologous MAtrix
Astyanax mexicanus	103034091	ASTMX11081
Poecilia formosa	103143007	POEFO10129
Callorhinchus milii	103179651	CALMI18298
Chlorocebus sabaeus	103222583	CHLSB06915
Carlito syrichta	103275974	CARSF02291
Ursus maritimus	103664958	URSMA03326
Nannospalax galili	103730574	NANGA05987
Rhinopithecus roxellana	104676151	RHIRO05200
Macaca nemestrina	105468134	MACNE39962
Mandrillus leucophaeus	105535331	MANLE09370