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MIRAGE
desmoglein 2
Summary
- Gene Symbol
-
- Dsg2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Calcium
- Cell adhesion
- Cell junction
- Cell membrane
- Cleavage on pair of basic residues
- Glycoprotein
- Metal-binding
- Palmitate
- Phosphoprotein
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| O55111 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| desmosome organization | ||
| desmosome organization | ||
| Purkinje myocyte development | ||
| Purkinje myocyte development | ||
| cell adhesion |
GO Hierarchy
biological process
biological regulation [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytoplasm | ||
| plasma membrane | ||
| cell surface | ||
| intercalated disc | ||
| intercalated disc |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| calcium ion binding | ||
| calcium ion binding | ||
| cell adhesion molecule binding | ||
| cell adhesion molecule binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Desmoglein-1
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| calcium ion binding |
| homophilic cell adhesion via plasma membrane adhesion molecules |
| InterPro |
|---|
| Cadherin conserved site |
| Cadherin-like superfamily |
| Cadherin-like |
| Catenin binding domain superfamily |
| Desmosomal cadherin |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050431 | arrhythmogenic right ventricular cardiomyopathy | |
| DOID:0060036 | intrinsic cardiomyopathy | |
| DOID:0110081 | arrhythmogenic right ventricular dysplasia 10 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 1828 | ZFIN:ZDB-GENE-091204-215 | ||
| 1829 | ZFIN:ZDB-GENE-091204-215 | HUMAN38010 | |
| 1830 | ZFIN:ZDB-GENE-091204-215 | ||
| 13510 | ZFIN:ZDB-GENE-091204-215 | ||
| 13511 | ZFIN:ZDB-GENE-091204-215 | ||
| 13512 | ZFIN:ZDB-GENE-091204-215 | ||
| 16769 | ZFIN:ZDB-GENE-091204-215 | ||
| 147409 | ZFIN:ZDB-GENE-091204-215 | ||
| 211924 | ZFIN:ZDB-GENE-091204-215 | ||
| 225256 | ZFIN:ZDB-GENE-091204-215 |
