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MIRAGE
beta-1,3-glucuronyltransferase 2

Summary
Gene Symbol
  • B3GAT2
Aliases
  • GlcAT-S
  • galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2
  • glucuronosyltransferase S
Organism
Homo sapiens (human)
NCBI Gene
135152
GGDB ID
HGNC
922
mRNA
map
  • 6q13
Protein
OMIM
KEGG Gene ID
hsa:135152
PubChem
135152
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Glycoprotein
  • Golgi apparatus
  • Manganese
  • Metal-binding
  • Reference proteome
  • Signal-anchor
  • Transferase
  • Transmembrane helix
Proteins
Displaying 1 entry
UniProt Protein Name
Q9NPZ5
  • Beta-1,3-glucuronyltransferase 2
  • GlcAT-D
  • UDP-glucuronosyltransferase S
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 4 entries
GO Term Evidence Code PMID
carbohydrate metabolic process
protein glycosylation
carbohydrate biosynthetic process
chondroitin sulfate proteoglycan biosynthetic process
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3
Functional Category
  • E: Amino acid transport and metabolism
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Displaying all 4 entries
Gene Ontology
chondroitin sulfate proteoglycan biosynthetic process
galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
metal ion binding
transferase activity
Displaying all 2 entries
InterPro
Glycosyl transferase, family 43
Nucleotide-diphospho-sugar transferases
GlycoGene Database (GGDB)
GGDB ID
gg156
Gene Symbol
  • B3GAT2
Reactions
Displaying 1 entry
Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
UDP-GlcA
G00055MO
R
G10271ZL
R
Displaying 1 entry
Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
UDP-GlcA
G00055MO
R
G10271ZL
R
Orthologous Gene
Displaying all 2 entries
Species Protein mRNA
Mus musculus NP_742122 NM_172124
Rattus norvegicus NP_072131 NM_022609
KEGG BRITE Database
Orthology
K10157
Name
galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 [EC:2.4.1.135]
References
Rhea

RHEA:56508

UDP-α-D-glucuronate
H+ + UDP
Enzyme
PMID

RHEA:24168

UDP-α-D-glucuronate
H+ + UDP
Enzyme
PMID
Disease
Disease Ontology
Displaying all 2 entries
DO ID Disease Name Source
DOID:5419 schizophrenia
DOID:9206 Barrett's esophagus
Ortholog
Displaying entries 81 - 85 of 85 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
116442132 CORMO19049
117018491 RHIFE11198
118283348 SCOMX08615
118905055 BALMU27557
122220075 PANLE15908
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025