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kallikrein 1-related peptidase b22

Summary

Gene Symbol

Klk1b22

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

13646

PubChem

13646

Alliance of Genome Resources

MGI:95291

Annotation

Keyword

Direct protein sequencing
Disulfide bond
Glycoprotein
Reference proteome
Serine protease
Signal
Zymogen

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q540N3
P15948	Beta-NGF-endopeptidase Epidermal growth factor-binding protein type A Glandular kallikrein K22 Nerve growth factor beta chain endopeptidase Tissue kallikrein 22

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
regulation of systemic arterial blood pressure	IBA
zymogen activation	IDA	9507064
zymogen activation	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

zymogen activation

protein maturation [inference]

protein processing [inference]

zymogen activation

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

zymogen activation

protein maturation [inference]

protein processing [inference]

zymogen activation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

zymogen activation

protein maturation [inference]

protein processing [inference]

zymogen activation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

zymogen activation

protein maturation [inference]

protein processing [inference]

zymogen activation

biological regulation [inference]

regulation of biological quality [inference]

regulation of blood pressure [inference]

regulation of systemic arterial blood pressure

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
acrosomal vesicle	ISO
extracellular space	ISO
extracellular space	IBA
nucleus	ISO
secretory granule	IBA

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

extracellular space

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

acrosomal vesicle

intracellular membrane-bounded organelle [inference]

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

acrosomal vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

acrosomal vesicle

apical part of cell

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
endopeptidase activity	ISO
serine-type endopeptidase activity	ISO
serine-type endopeptidase activity	IBA
serine-type endopeptidase activity	IEA
peptidase activity	IDA	9507064

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity

endopeptidase activity

serine-type endopeptidase activity

serine-type peptidase activity

serine-type endopeptidase activity

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

serine hydrolase activity [inference]

serine-type peptidase activity

serine-type endopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity

endopeptidase activity

serine-type endopeptidase activity

serine-type peptidase activity

serine-type endopeptidase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

isoform A

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
proteolysis
serine-type endopeptidase activity

Displaying **all 6** entries
InterPro
Peptidase S1, PA clan, chymotrypsin-like fold
Peptidase S1, PA clan
Peptidase S1A, chymotrypsin family
Serine proteases, trypsin domain
Serine proteases, trypsin family, histidine active site
Serine proteases, trypsin family, serine active site