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carboxypeptidase N subunit 1

Summary

Gene Symbol

CPN1

Organism

Homo sapiens (human)

External Links

NCBI Gene

1369

PubChem

1369

Alliance of Genome Resources

HGNC:2312

Annotation

Keyword

3D-structure
Carboxypeptidase
Direct protein sequencing
Disease variant
Disulfide bond
Glycoprotein
Metal-binding
Metalloprotease
Reference proteome
Secreted
Signal
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
P15169	Anaphylatoxin inactivator Arginine carboxypeptidase Carboxypeptidase N polypeptide 1 Carboxypeptidase N small subunit Kininase-1 Lysine carboxypeptidase Plasma carboxypeptidase B Serum carboxypeptidase N

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
peptide metabolic process	IBA
bradykinin catabolic process	IEA
protein processing	IBA
protein catabolic process	IEA
response to glucocorticoid	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

peptide metabolic process

peptide catabolic process [inference]

bradykinin catabolic process

organonitrogen compound metabolic process [inference]

peptide metabolic process

peptide catabolic process [inference]

bradykinin catabolic process

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein catabolic process

protein maturation [inference]

protein processing

organonitrogen compound catabolic process [inference]

protein catabolic process

peptide catabolic process [inference]

bradykinin catabolic process

catabolic process [inference]

cellular catabolic process [inference]

peptide catabolic process [inference]

bradykinin catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process

peptide catabolic process [inference]

bradykinin catabolic process

cellular metabolic process [inference]

cellular catabolic process [inference]

peptide catabolic process [inference]

bradykinin catabolic process

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein catabolic process

protein maturation [inference]

protein processing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein catabolic process

protein maturation [inference]

protein processing

organonitrogen compound metabolic process [inference]

peptide metabolic process

peptide catabolic process [inference]

bradykinin catabolic process

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein catabolic process

protein maturation [inference]

protein processing

organonitrogen compound catabolic process [inference]

protein catabolic process

peptide catabolic process [inference]

bradykinin catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process

peptide catabolic process [inference]

bradykinin catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular catabolic process [inference]

peptide catabolic process [inference]

bradykinin catabolic process

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to organic cyclic compound [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to lipid [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular region	TAS
extracellular space	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 3** entries
GO Term	Evidence Code	PMID
metallocarboxypeptidase activity	IBA
protein binding	IPI	32814053
zinc ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

metallopeptidase activity [inference]

metalloexopeptidase activity [inference]

metallocarboxypeptidase activity

exopeptidase activity [inference]

carboxypeptidase activity [inference]

metallocarboxypeptidase activity

metalloexopeptidase activity [inference]

metallocarboxypeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

metallopeptidase activity [inference]

metalloexopeptidase activity [inference]

metallocarboxypeptidase activity

exopeptidase activity [inference]

carboxypeptidase activity [inference]

metallocarboxypeptidase activity

metalloexopeptidase activity [inference]

metallocarboxypeptidase activity

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

carboxypeptidase D

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 5** entries
Gene Ontology
carboxypeptidase activity
metallocarboxypeptidase activity
peptide metabolic process
proteolysis
zinc ion binding

Displaying **all 2** entries
InterPro
Carboxypeptidase-like, regulatory domain superfamily
Peptidase M14, carboxypeptidase A

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0111583	carboxypeptidase N deficiency	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 91 in total

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Last »
Species	Gene ID	Alliance of Genome Resources
Caenorhabditis elegans	1363	WB:WBGene00001189
Caenorhabditis elegans	1368	WB:WBGene00012073
Xenopus tropicalis	1369	Xenbase:XB-GENE-967670
Caenorhabditis elegans	8532	WB:WBGene00001189
Caenorhabditis elegans	11568	WB:WBGene00001189
Caenorhabditis elegans	12876	WB:WBGene00001189
Caenorhabditis elegans	25669	WB:WBGene00001189
Caenorhabditis elegans	30998	WB:WBGene00012073
Caenorhabditis elegans	55987	WB:WBGene00001189
Caenorhabditis elegans	56264	WB:WBGene00001189

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Acknowledgements