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glutamyl aminopeptidase

Summary

Gene Symbol

Enpep

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

13809

PubChem

13809

Alliance of Genome Resources

MGI:106645

Annotation

Keyword

Aminopeptidase
Calcium
Cell membrane
Direct protein sequencing
Disulfide bond
Glycoprotein
Metal-binding
Metalloprotease
Reference proteome
Signal-anchor
Transmembrane helix
Zinc

Proteins

Displaying **all 4** entries
UniProt	Protein Name
P16406	Aminopeptidase A BP-1/6C3 antigen
Q8CD51	Aminopeptidase A
Q52JJ6
Q6P3C1

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
angiogenesis	IMP	14998491
angiotensin maturation	IDA	19228697
angiotensin maturation	IMP	16889841
regulation of systemic arterial blood pressure by renin-angiotensin	ISS
regulation of systemic arterial blood pressure by renin-angiotensin	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

peptide metabolic process [inference]

peptide hormone processing [inference]

angiotensin maturation

peptide catabolic process

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide hormone processing [inference]

angiotensin maturation

peptide catabolic process

protein metabolic process [inference]

proteolysis

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

organonitrogen compound catabolic process [inference]

peptide catabolic process

catabolic process [inference]

cellular catabolic process [inference]

peptide catabolic process

organic substance catabolic process [inference]

organonitrogen compound catabolic process [inference]

peptide catabolic process

hormone metabolic process [inference]

peptide hormone processing [inference]

angiotensin maturation

cellular metabolic process [inference]

cellular catabolic process [inference]

peptide catabolic process

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide hormone processing [inference]

angiotensin maturation

peptide catabolic process

protein metabolic process [inference]

proteolysis

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

organonitrogen compound catabolic process [inference]

peptide catabolic process

organic substance catabolic process [inference]

organonitrogen compound catabolic process [inference]

peptide catabolic process

cellular process [inference]

cell population proliferation

epithelial cell proliferation [inference]

endothelial cell proliferation [inference]

vascular endothelial cell proliferation

cellular metabolic process [inference]

cellular catabolic process [inference]

peptide catabolic process

cell motility [inference]

cell migration

multicellular organismal process [inference]

system process [inference]

endocrine process [inference]

regulation of systemic arterial blood pressure by hormone [inference]

regulation of systemic arterial blood pressure by renin-angiotensin

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

anatomical structure development [inference]

glomerulus development

biological regulation [inference]

regulation of biological quality [inference]

regulation of blood pressure

regulation of systemic arterial blood pressure [inference]

regulation of systemic arterial blood pressure mediated by a chemical signal [inference]

regulation of systemic arterial blood pressure by hormone [inference]

regulation of systemic arterial blood pressure by renin-angiotensin

regulation of hormone levels [inference]

hormone metabolic process [inference]

peptide hormone processing [inference]

angiotensin maturation

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
extracellular space	IBA
cytoplasm	IBA
plasma membrane	ISS
plasma membrane	ISO
plasma membrane	TAS	14998491

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

apical plasma membrane

cell projection membrane [inference]

brush border membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

apical part of cell

side of membrane [inference]

external side of plasma membrane

cluster of actin-based cell projections [inference]

brush border

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
aminopeptidase activity	ISS
aminopeptidase activity	ISO
obsolete glutamyl aminopeptidase activity	IEA
peptidase activity	IDA	14998491
metallopeptidase activity	IDA	19228697

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity

metallopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

exopeptidase activity [inference]

aminopeptidase activity

metalloaminopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity

metallopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

exopeptidase activity [inference]

aminopeptidase activity

metalloaminopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

binding [inference]

amide binding [inference]

peptide binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

aminopeptidase A

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
V: Defense mechanisms

Displaying **all 9** entries
Gene Ontology
aminopeptidase activity
hydrolase activity
metal ion binding
metalloaminopeptidase activity
metallopeptidase activity
peptide binding
peptide catabolic process
proteolysis
zinc ion binding

Displaying **all 7** entries
InterPro
Aminopeptidase N-like , N-terminal domain superfamliy
Aminopeptidase N-like , N-terminal domain
Aminopeptidase N-type
ERAP1-like C-terminal domain
Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
Peptidase M1, membrane alanine aminopeptidase
Peptidase M4/M1, CTD superfamily

Ortholog

Displaying entries **1 - 10** of 96 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	290	SGD:S000001399
Homo sapiens	2028	Xenbase:XB-GENE-977050	HUMAN77018
Saccharomyces cerevisiae S288C	4012	SGD:S000001399
Xenopus tropicalis	13809	Xenbase:XB-GENE-977050
Saccharomyces cerevisiae S288C	16790	SGD:S000001399
Saccharomyces cerevisiae S288C	29953	SGD:S000001399
Saccharomyces cerevisiae S288C	51752	SGD:S000001399
Rattus norvegicus	64017	Xenbase:XB-GENE-977050	RATNO25323
Saccharomyces cerevisiae S288C	64167	SGD:S000001399
Saccharomyces cerevisiae S288C	80898	SGD:S000001399