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exostosin glycosyltransferase 1

Summary

Gene Symbol

Ext1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

14042

KEGG Gene ID

mmu:14042

PubChem

14042

Alliance of Genome Resources

MGI:894663

Annotation

Keyword

Disulfide bond
Endoplasmic reticulum
Glycoprotein
Glycosyltransferase
Golgi apparatus
Manganese
Metal-binding
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q3V1P4	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase
P97464	Exostosin glycosyltransferase 1 Multiple exostoses protein 1 homolog N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **11 - 15** of **114** in total

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GO Term	Evidence Code	PMID
chondrocyte hypertrophy	IMP	23958822
endochondral bone growth	IMP	23192691
glycosaminoglycan biosynthetic process	ISO
protein glycosylation	IEA
vacuole organization	IMP	18480751

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

inflammatory response to antigenic stimulus [inference]

acute inflammatory response to antigenic stimulus [inference]

hypersensitivity

antigen processing and presentation

leukocyte migration [inference]

mononuclear cell migration [inference]

dendritic cell migration

lymphocyte migration [inference]

lymphocyte migration into lymphoid organs

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

heparin biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process

heparin biosynthetic process

mucopolysaccharide metabolic process [inference]

heparin metabolic process

heparin biosynthetic process

chondroitin sulfate metabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan biosynthetic process

protein catabolic process

protein modification process [inference]

protein glycosylation

organonitrogen compound catabolic process [inference]

protein catabolic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

heparin biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan biosynthetic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

heparin biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan biosynthetic process

gene expression

cytokine production [inference]

chemokine production

sulfur compound biosynthetic process [inference]

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

heparin biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan biosynthetic process

gene expression

cytokine production [inference]

chemokine production

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

heparin biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

heparin biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan biosynthetic process

cellular metabolic process [inference]

sulfur compound metabolic process [inference]

heparin metabolic process

heparin biosynthetic process

chondroitin sulfate metabolic process

sulfur compound biosynthetic process [inference]

sulfation

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

heparin biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan biosynthetic process

gene expression

cytokine production [inference]

chemokine production

sulfur compound biosynthetic process [inference]

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan biosynthetic process

protein catabolic process

protein modification process [inference]

protein glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

heparin biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process

heparin biosynthetic process

mucopolysaccharide metabolic process [inference]

heparin metabolic process

heparin biosynthetic process

chondroitin sulfate metabolic process

macromolecule catabolic process [inference]

protein catabolic process

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

heparin biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan biosynthetic process

gene expression

cytokine production [inference]

chemokine production

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan biosynthetic process

protein catabolic process

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

heparin biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process

heparin biosynthetic process

mucopolysaccharide metabolic process [inference]

heparin metabolic process

heparin biosynthetic process

chondroitin sulfate metabolic process

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

heparin biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan biosynthetic process

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

heparin biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process

heparin biosynthetic process

mucopolysaccharide metabolic process [inference]

heparin metabolic process

heparin biosynthetic process

chondroitin sulfate metabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan biosynthetic process

protein catabolic process

protein modification process [inference]

protein glycosylation

organonitrogen compound catabolic process [inference]

protein catabolic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

heparin biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan biosynthetic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

heparin biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan biosynthetic process

gene expression

cytokine production [inference]

chemokine production

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

heparin biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

heparin biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan biosynthetic process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, glutamatergic

cell adhesion

cell adhesion mediated by integrin

cell-cell adhesion [inference]

leukocyte cell-cell adhesion [inference]

leukocyte adhesion to vascular endothelial cell [inference]

signal transduction [inference]

cell surface receptor signaling pathway

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

fibroblast growth factor receptor signaling pathway

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

BMP signaling pathway

smoothened signaling pathway

smoothened signaling pathway involved in lung development

Wnt signaling pathway [inference]

canonical Wnt signaling pathway

cell recognition [inference]

neuron recognition [inference]

dendrite self-avoidance

cell population proliferation

chondrocyte proliferation

cell growth [inference]

developmental cell growth [inference]

chondrocyte hypertrophy

cellular metabolic process [inference]

sulfur compound metabolic process [inference]

heparin metabolic process

heparin biosynthetic process

chondroitin sulfate metabolic process

sulfur compound biosynthetic process [inference]

sulfation

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

heparin biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan biosynthetic process

gene expression

cytokine production [inference]

chemokine production

sulfur compound biosynthetic process [inference]

cellular developmental process [inference]

cell differentiation [inference]

chondrocyte differentiation

hematopoietic progenitor cell differentiation

hematopoietic stem cell differentiation

epithelial cell differentiation [inference]

columnar/cuboidal epithelial cell differentiation [inference]

glandular epithelial cell differentiation

epithelial cell differentiation involved in kidney development [inference]

glomerular epithelial cell differentiation [inference]

podocyte differentiation

mesenchymal cell differentiation [inference]

stem cell differentiation [inference]

cell differentiation involved in kidney development [inference]

epithelial cell differentiation involved in kidney development [inference]

glomerular epithelial cell differentiation [inference]

podocyte differentiation

renal filtration cell differentiation [inference]

podocyte differentiation

cell fate commitment

cell motility [inference]

cell migration [inference]

hematopoietic stem cell migration [inference]

hematopoietic stem cell migration to bone marrow

leukocyte migration [inference]

mononuclear cell migration [inference]

dendritic cell migration

lymphocyte migration [inference]

lymphocyte migration into lymphoid organs

cell division [inference]

stem cell division

cellular component organization or biogenesis [inference]

cellular component organization

organelle organization [inference]

vacuole organization

cellular component assembly [inference]

protein-containing complex assembly

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development

neuron projection guidance [inference]

axon guidance

cell junction organization [inference]

cell-cell junction organization [inference]

tight junction organization

extracellular structure organization [inference]

extracellular matrix organization [inference]

protein-containing complex organization [inference]

protein-containing complex assembly

external encapsulating structure organization [inference]

extracellular matrix organization [inference]

supramolecular fiber organization [inference]

collagen fibril organization

multicellular organismal process [inference]

ossification

replacement ossification [inference]

endochondral ossification

ossification involved in bone maturation

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube [inference]

epithelial tube branching involved in lung morphogenesis

cytokine production [inference]

chemokine production

system process [inference]

circulatory system process [inference]

heart process [inference]

heart contraction

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

vasodilation

pattern specification process [inference]

regionalization [inference]

specification of animal organ identity [inference]

heart field specification

behavior [inference]

molting cycle process [inference]

hair cycle process

hair follicle morphogenesis

multicellular organismal response to stress [inference]

fear response

multicellular organism growth

organ growth [inference]

bone growth

endochondral bone growth

tissue remodeling [inference]

blood vessel remodeling

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

hematopoietic stem cell homeostasis

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

bone resorption

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level water homeostasis

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube [inference]

epithelial tube branching involved in lung morphogenesis

animal organ morphogenesis [inference]

bone morphogenesis

endochondral bone morphogenesis

membrane bone morphogenesis [inference]

perichondral bone morphogenesis

hair follicle morphogenesis

tube morphogenesis [inference]

branching morphogenesis of an epithelial tube [inference]

epithelial tube branching involved in lung morphogenesis

limb joint morphogenesis

embryonic morphogenesis

gastrulation

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube [inference]

epithelial tube branching involved in lung morphogenesis

anatomical structure development [inference]

tissue development [inference]

nerve development [inference]

cranial nerve development [inference]

optic nerve development

animal organ development [inference]

brain development

gland development [inference]

cartilage development [inference]

cartilage development involved in endochondral bone morphogenesis

system development [inference]

skeletal system development [inference]

embryonic skeletal system development [inference]

embryonic skeletal joint development

cellular developmental process [inference]

cell differentiation [inference]

chondrocyte differentiation

hematopoietic progenitor cell differentiation

hematopoietic stem cell differentiation

epithelial cell differentiation [inference]

columnar/cuboidal epithelial cell differentiation [inference]

glandular epithelial cell differentiation

epithelial cell differentiation involved in kidney development [inference]

glomerular epithelial cell differentiation [inference]

podocyte differentiation

mesenchymal cell differentiation [inference]

stem cell differentiation [inference]

cell differentiation involved in kidney development [inference]

epithelial cell differentiation involved in kidney development [inference]

glomerular epithelial cell differentiation [inference]

podocyte differentiation

renal filtration cell differentiation [inference]

podocyte differentiation

cell fate commitment

growth [inference]

cell growth [inference]

developmental cell growth [inference]

chondrocyte hypertrophy

developmental growth [inference]

multicellular organism growth

organ growth [inference]

bone growth

endochondral bone growth

developmental cell growth [inference]

chondrocyte hypertrophy

developmental growth involved in morphogenesis

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

hematopoietic stem cell homeostasis

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

bone resorption

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level water homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

monoatomic cation homeostasis [inference]

sodium ion homeostasis

inorganic ion homeostasis [inference]

sodium ion homeostasis

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level water homeostasis

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus

cellular response to virus

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response [inference]

inflammatory response to antigenic stimulus [inference]

acute inflammatory response to antigenic stimulus [inference]

hypersensitivity

acute inflammatory response [inference]

acute inflammatory response to antigenic stimulus [inference]

hypersensitivity

response to wounding [inference]

wound healing

multicellular organismal response to stress [inference]

fear response

immune response [inference]

inflammatory response to antigenic stimulus [inference]

acute inflammatory response to antigenic stimulus [inference]

hypersensitivity

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus

cellular response to virus

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus

cellular response to virus

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

response to light intensity

response to endogenous stimulus [inference]

response to growth factor

cellular response to growth factor stimulus [inference]

response to BMP [inference]

cellular response to BMP stimulus

response to fibroblast growth factor [inference]

cellular response to fibroblast growth factor stimulus

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

response to heparin

response to cytokine [inference]

response to leukemia inhibitory factor

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to heparin

response to oxygen-containing compound [inference]

response to heparin

localization [inference]

establishment of localization [inference]

transport [inference]

fluid transport

biological process involved in intraspecies interaction between organisms [inference]

social behavior

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

regulation of tumor necrosis factor-mediated signaling pathway

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, glutamatergic

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

regulation of tumor necrosis factor-mediated signaling pathway

regulation of response to cytokine stimulus [inference]

regulation of cytokine-mediated signaling pathway [inference]

regulation of tumor necrosis factor-mediated signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

fibroblast growth factor receptor signaling pathway

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

BMP signaling pathway

smoothened signaling pathway

smoothened signaling pathway involved in lung development

Wnt signaling pathway [inference]

canonical Wnt signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

regulation of tumor necrosis factor-mediated signaling pathway

regulation of biological quality [inference]

regulation of blood pressure

regulation of body fluid levels [inference]

multicellular organismal-level water homeostasis

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

vasodilation

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
Golgi membrane	IEA
endoplasmic reticulum	ISO
endoplasmic reticulum membrane	IDA	9620772
Golgi apparatus	ISO
Golgi apparatus	IDA	10639137

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

bounding membrane of organelle [inference]

Golgi membrane

cell junction [inference]

synapse

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
acetylglucosaminyltransferase activity	IBA
glucuronosyltransferase activity	IBA
glycosyltransferase activity	IMP	10926768
protein homodimerization activity	ISO
protein homodimerization activity	IEA