GlyCosmos Portal

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stereocilin

Summary

Gene Symbol

Strc

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

140476

PubChem

140476

Alliance of Genome Resources

MGI:2153816

Annotation

Keyword

Cilium
Glycoprotein
Hearing
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8VIM6

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
cell-matrix adhesion	IBA
sensory perception of sound	ISO	11687802
protein localization	IMP	31776257
detection of mechanical stimulus involved in sensory perception of sound	IMP	18849963
auditory receptor cell stereocilium organization	IMP	18849963 21165971

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-substrate adhesion [inference]

cell-matrix adhesion

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

inner ear receptor cell stereocilium organization

auditory receptor cell stereocilium organization

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of mechanical stimulus [inference]

sensory perception of sound

detection of mechanical stimulus involved in sensory perception of sound

response to stimulus [inference]

response to external stimulus [inference]

detection of external stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

response to mechanical stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

response to abiotic stimulus [inference]

detection of abiotic stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

response to mechanical stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

detection of stimulus [inference]

detection of external stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

detection of abiotic stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

detection of stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization

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GO Term	Evidence Code	PMID
cell surface	IBA
cell surface	IEA
stereocilium tip	IDA	18849963 21165971 24920589 31448880
stereocilium tip	IBA
kinocilium	IDA	21165971

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium [inference]

non-motile cilium [inference]

9+2 non-motile cilium [inference]

kinocilium

neuron projection [inference]

kinocilium

organelle [inference]

membrane-bounded organelle [inference]

cilium [inference]

non-motile cilium [inference]

9+2 non-motile cilium [inference]

kinocilium

Displaying 1 entry
GO Term	Evidence Code	PMID
molecular_function	ND

GO Hierarchy

molecular function

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Stereocilin

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
cell-matrix adhesion

Displaying 1 entry
InterPro
Stereocilin-related

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110471	autosomal recessive nonsyndromic deafness 16	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	140476	ZFIN:ZDB-GENE-110411-215
Homo sapiens	161497	ZFIN:ZDB-GENE-110411-215	HUMAN22711
Bos taurus	528436		BOVIN16858
Rattus norvegicus	691937		RATNO28482
Pan troglodytes	742658		PANTR10153
Monodelphis domestica	100011646		MONDO06168
Equus caballus	100056242		HORSE16949
Callithrix jacchus	100393330		CALJA01439
Pongo abelii	100434832		PONAB08785
Pongo abelii	100436701		PONAB08785

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements