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protein phosphatase 1, regulatory subunit 3A

Summary

Gene Symbol

Ppp1r3a

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

140491

PubChem

140491

Alliance of Genome Resources

MGI:2153588

Annotation

Keyword

Direct protein sequencing
Glycogen metabolism
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q99MR9	Protein phosphatase 1 glycogen-associated regulatory subunit Protein phosphatase type-1 glycogen targeting subunit

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
regulation of glycogen biosynthetic process	IBA
glycogen metabolic process	TAS	11361130

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

cellular process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process

regulation of carbohydrate biosynthetic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process

regulation of generation of precursor metabolites and energy [inference]

regulation of glycogen metabolic process [inference]

regulation of glycogen biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process

regulation of polysaccharide metabolic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process

regulation of glycogen metabolic process [inference]

regulation of glycogen biosynthetic process

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of polysaccharide metabolic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process

regulation of glycogen metabolic process [inference]

regulation of glycogen biosynthetic process

regulation of carbohydrate biosynthetic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process

regulation of generation of precursor metabolites and energy [inference]

regulation of glycogen metabolic process [inference]

regulation of glycogen biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein phosphatase type 1 complex	IBA
membrane	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

phosphatase complex [inference]

protein serine/threonine phosphatase complex [inference]

protein phosphatase type 1 complex

cellular anatomical entity [inference]

membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein phosphatase 1 binding	IBA
glycogen binding	IBA
protein serine/threonine phosphatase activity	ISO	11361130

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

phosphoprotein phosphatase activity [inference]

protein serine/threonine phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity [inference]

protein serine/threonine phosphatase activity

binding [inference]

protein binding [inference]

enzyme binding [inference]

phosphatase binding [inference]

protein phosphatase binding [inference]

protein phosphatase 1 binding

carbohydrate binding [inference]

polysaccharide binding [inference]

glycogen binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

protein phosphatase 1 regulatory subunit 3A

Functional Category

G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis
K: Transcription

Displaying **all 3** entries
Gene Ontology
glycogen binding
protein phosphatase 1 binding
regulation of glycogen biosynthetic process

Displaying **all 2** entries
InterPro
CBM21 (carbohydrate binding type-21) domain
CBM21 domain superfamily

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:9352	type 2 diabetes mellitus	Alliance of Genome Resources
DOID:9993	hypoglycemia	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **103** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	5506		HGNC:9291	HUMAN90896
Pan troglodytes	463666			PANTR41207
Canis lupus familiaris	482411			CANLF03838
Rattus norvegicus	500036	10116_1:001c9c	RGD:1561312	RATNO30270
Macaca mulatta	703562			MACMU33151
Bos taurus	784877			BOVIN28015
Saccharomyces cerevisiae S288C	850979		SGD:S000004263
Saccharomyces cerevisiae S288C	854350		SGD:S000005704
Saccharomyces cerevisiae S288C	854766		SGD:S000001307
Saccharomyces cerevisiae S288C	856781		SGD:S000000856

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024