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sideroflexin 1

Summary

Gene Symbol

Sfxn1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

14057

PubChem

14057

Alliance of Genome Resources

MGI:2137677

Annotation

Keyword

Acetylation
Amino-acid transport
Direct protein sequencing
Mitochondrion inner membrane
One-carbon metabolism
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q99JR1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
iron ion transport	IMP TAS	11274051
L-alanine transport	ISO ISS
erythrocyte differentiation	IMP	11274051
ion transmembrane transport	IEA
L-serine transport	ISO ISS

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

one-carbon metabolic process

small molecule metabolic process [inference]

one-carbon metabolic process

cellular process [inference]

cellular metabolic process [inference]

one-carbon metabolic process

cellular developmental process [inference]

cell differentiation [inference]

myeloid cell differentiation [inference]

erythrocyte differentiation

transmembrane transport [inference]

monoatomic ion transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

serine import into mitochondrion

mitochondrial transmembrane transport [inference]

serine import into mitochondrion

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

myeloid cell differentiation [inference]

erythrocyte differentiation

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

transition metal ion transport [inference]

iron ion transport

monoatomic ion transmembrane transport

mitochondrial transport [inference]

mitochondrial transmembrane transport [inference]

serine import into mitochondrion

transmembrane transport [inference]

monoatomic ion transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

serine import into mitochondrion

mitochondrial transmembrane transport [inference]

serine import into mitochondrion

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

serine import into mitochondrion

neutral amino acid transport [inference]

alanine transport [inference]

L-alanine transport

serine transport [inference]

L-amino acid transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

serine import into mitochondrion

organic acid transport [inference]

carboxylic acid transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

serine import into mitochondrion

neutral amino acid transport [inference]

alanine transport [inference]

L-alanine transport

serine transport [inference]

L-amino acid transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

serine import into mitochondrion

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

serine import into mitochondrion

nitrogen compound transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

serine import into mitochondrion

neutral amino acid transport [inference]

alanine transport [inference]

L-alanine transport

serine transport [inference]

L-amino acid transport [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
mitochondrial inner membrane	HDA IBA ISO ISS	12865426
mitochondrion	HDA IDA ISO	11274051 14651853 18614015

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 5** entries
GO Term	Evidence Code	PMID
L-serine transmembrane transporter activity	ISO ISS
ion transmembrane transporter activity	IEA
monoatomic ion transmembrane transporter activity	IEA
transmembrane transporter activity	IBA
L-alanine transmembrane transporter activity	ISO ISS

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity

organic acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity [inference]

neutral L-amino acid transmembrane transporter activity [inference]

alanine transmembrane transporter activity [inference]

L-alanine transmembrane transporter activity

L-amino acid transmembrane transporter activity [inference]

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity [inference]

neutral L-amino acid transmembrane transporter activity [inference]

alanine transmembrane transporter activity [inference]

L-alanine transmembrane transporter activity

L-amino acid transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

sideroflexin-1

Functional Category

H: Coenzyme transport and metabolism
I: Lipid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
monoatomic ion transmembrane transporter activity
monoatomic ion transport
serine import into mitochondrion

Displaying 1 entry
InterPro
Tricarboxylate/iron carrier

Ortholog

Displaying entries **1 - 10** of **114** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	40552		FB:FBgn0037239
Homo sapiens	94081		HGNC:16085	HUMAN82347
Caenorhabditis elegans	174708		WB:WBGene00009513
Caenorhabditis elegans	180055		WB:WBGene00012402
Caenorhabditis elegans	181807		WB:WBGene00007080
Caenorhabditis elegans	183547		WB:WBGene00008137
Rattus norvegicus	364678	10116_1:004c57	RGD:1308482	RATNO12588
Danio rerio	445143		ZFIN:ZDB-GENE-040801-45	DANRE07625
Pan troglodytes	471749			PANTR36869
Canis lupus familiaris	489109			CANLF14798