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BMP/retinoic acid inducible neural specific 1

Summary

Gene Symbol

Brinp1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

140610

PubChem

140610

Alliance of Genome Resources

RGD:708519

Annotation

Keyword

Cytoplasm
Glycoprotein
Growth arrest
Neurogenesis
Reference proteome
Signal

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q925T8	Deleted in bladder cancer protein 1 homolog
A6J803
G3V6Q9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 20 in total

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GO Term	Evidence Code	PMID
brain development	IEA ISO
proteasomal protein catabolic process	IEA ISO
vocalization behavior	IEA ISO
homeostasis of number of cells within a tissue	IEA ISO
positive regulation of neuron differentiation	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process

macromolecule biosynthetic process [inference]

gene expression

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular process [inference]

cell population proliferation

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis

neuron differentiation [inference]

central nervous system neuron differentiation

cell development [inference]

neuron development [inference]

central nervous system neuron development

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to retinoic acid

cellular response to oxygen-containing compound [inference]

cellular response to retinoic acid

reproductive process [inference]

reproductive behavior [inference]

parental behavior [inference]

maternal behavior

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

memory [inference]

short-term memory

behavior [inference]

behavioral defense response [inference]

behavioral fear response

learning or memory [inference]

memory [inference]

short-term memory

reproductive behavior [inference]

parental behavior [inference]

maternal behavior

multicellular organismal response to stress [inference]

fear response [inference]

behavioral fear response

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

homeostasis of number of cells within a tissue

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

homeostasis of number of cells within a tissue

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

neuron development [inference]

central nervous system neuron development

animal organ development [inference]

brain development

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis

neuron differentiation [inference]

central nervous system neuron differentiation

cell development [inference]

neuron development [inference]

central nervous system neuron development

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

homeostasis of number of cells within a tissue

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

homeostasis of number of cells within a tissue

response to stimulus [inference]

response to stress [inference]

defense response [inference]

behavioral defense response [inference]

behavioral fear response

multicellular organismal response to stress [inference]

fear response [inference]

behavioral fear response

response to chemical [inference]

response to organic substance [inference]

response to lipid [inference]

response to retinoic acid [inference]

cellular response to retinoic acid

cellular response to lipid [inference]

cellular response to retinoic acid

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to retinoic acid

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to retinoic acid

cellular response to oxygen-containing compound [inference]

cellular response to retinoic acid

response to oxygen-containing compound [inference]

response to retinoic acid [inference]

cellular response to retinoic acid

cellular response to oxygen-containing compound [inference]

cellular response to retinoic acid

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to retinoic acid

cellular response to oxygen-containing compound [inference]

cellular response to retinoic acid

biological process involved in intraspecies interaction between organisms [inference]

social behavior

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis

negative regulation of cell cycle

negative regulation of mitotic cell cycle

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis

negative regulation of nervous system development [inference]

negative regulation of neurogenesis

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis

regulation of developmental process [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of neuron differentiation [inference]

positive regulation of neuron differentiation

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis

regulation of neurogenesis [inference]

negative regulation of neurogenesis

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis

negative regulation of nervous system development [inference]

negative regulation of neurogenesis

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

negative regulation of neurogenesis

negative regulation of nervous system development [inference]

negative regulation of neurogenesis

regulation of cellular process [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of neuron differentiation [inference]

positive regulation of neuron differentiation

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis

regulation of neurogenesis [inference]

negative regulation of neurogenesis

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

negative regulation of cellular process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis

negative regulation of cell cycle

negative regulation of mitotic cell cycle

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

negative regulation of mitotic cell cycle

negative regulation of cell cycle

negative regulation of mitotic cell cycle

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

negative regulation of neurogenesis

negative regulation of nervous system development [inference]

negative regulation of neurogenesis

regulation of biological quality [inference]

regulation of protein stability [inference]

protein stabilization

Displaying **all 5** entries
GO Term	Evidence Code	PMID
neuronal cell body	IBA
dendrite	IBA
synapse	ISO
cytoplasm	IBA IEA ISO ISS
glutamatergic synapse	IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

cell junction [inference]

synapse

glutamatergic synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

cell body [inference]

neuronal cell body

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

BMP/retinoic acid-inducible neural-specific protein

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
cellular response to retinoic acid
negative regulation of cell cycle
negative regulation of mitotic cell cycle
nervous system development
positive regulation of neuron differentiation

Displaying **all 2** entries
InterPro
BMP/retinoic acid-inducible neural-specific protein
Membrane attack complex component/perforin (MACPF) domain

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0060041	autism spectrum disorder	Alliance of Genome Resources
DOID:1094	attention deficit hyperactivity disorder	Alliance of Genome Resources

Ortholog

Displaying entries **101 - 110** of **115** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Microtus oregoni	121433840	111838_0:004600
Dipodomys spectabilis	122107124	105255_0:001279
Panthera leo	122205347		PANLE26317
Marmota monax	124097309	9995_0:00189c
Sciurus carolinensis	124964565	30640_0:0040bf
Perognathus longimembris pacificus	125356272	214514_0:00025c
Myodes glareolus	125416322	447135_0:003550
Microtus fortis	126493295	100897_0:004cc8
Acomys russatus	127204295	60746_0:000389
Phodopus roborovskii	127224885	109678_0:002327

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements