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N-acetylneuraminic acid phosphatase

Summary

Gene Symbol

NANP

Aliases

MGC26833
dJ694B14.3

Organism

Homo sapiens (human)

External Links

NCBI Gene

140838

HGNC

16140

KEGG Gene ID

hsa:140838

PubChem

140838

Alliance of Genome Resources

HGNC:16140

Annotation

Keyword

3D-structure
Carbohydrate metabolism
Hydrolase
Magnesium
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8TBE9	Haloacid dehalogenase-like hydrolase domain-containing protein 4 Neu5Ac-9-Pase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
N-acetylneuraminate biosynthetic process	IBA IDA	16237198
dephosphorylation	IBA
N-acetylglucosamine biosynthetic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

amide metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate biosynthetic process

amide biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

organonitrogen compound metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate biosynthetic process

organonitrogen compound biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

amino sugar biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

glucosamine-containing compound biosynthetic process [inference]

N-acetylglucosamine biosynthetic process

organonitrogen compound biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate biosynthetic process

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate biosynthetic process

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate biosynthetic process

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

carbohydrate derivative metabolic process [inference]

amino sugar metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate biosynthetic process

amino sugar biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

glucosamine-containing compound biosynthetic process [inference]

N-acetylglucosamine biosynthetic process

glucosamine-containing compound metabolic process [inference]

N-acetylglucosamine metabolic process [inference]

N-acetylglucosamine biosynthetic process

glucosamine-containing compound biosynthetic process [inference]

N-acetylglucosamine biosynthetic process

carbohydrate derivative biosynthetic process [inference]

amino sugar biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

glucosamine-containing compound biosynthetic process [inference]

N-acetylglucosamine biosynthetic process

organonitrogen compound metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate biosynthetic process

organonitrogen compound biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

amino sugar biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

glucosamine-containing compound biosynthetic process [inference]

N-acetylglucosamine biosynthetic process

organonitrogen compound biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate biosynthetic process

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytosol
cellular_component	ND

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying 1 entry
GO Term	Evidence Code	PMID
N-acylneuraminate-9-phosphatase activity	IBA IDA	16237198

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

N-acylneuraminate-9-phosphatase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K01097

Name

N-acylneuraminate-9-phosphatase [EC:3.1.3.29]

References

16237198

Rhea

H₂O + an N-acylneuraminate 9-phosphate

phosphate + an N-acylneuraminate

Enzyme

3.1.3.29

PMID

16237198

Disease

Disease Ontology

Displaying **all 7** entries
DO ID	Disease Name	Source
DOID:1107	esophageal carcinoma	DisGeNET
DOID:12365	malaria	DisGeNET
DOID:1443	cerebral degeneration	DisGeNET
DOID:162	cancer	DisGeNET
DOID:5041	esophageal cancer	DisGeNET
DOID:5672	large intestine cancer	DisGeNET
DOID:9256	colorectal cancer	DisGeNET

Ortholog

Displaying entries **11 - 20** of 76 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Sparus aurata	115596990		SPAAU09635
Xenopus laevis	414493	Xenbase:XB-GENE-1008553
Xenopus tropicalis	549940	Xenbase:XB-GENE-1008548
Chrysemys picta bellii	101940927		CHRPI33958
Pseudonaja textilis	113433133		PSETE03393
Erinaceus europaeus	103126407		ERIEU05086
Callithrix jacchus	100410318		CALJA34895
Macaca fascicularis	102129164		MACFA00999
Macaca mulatta	706491		MACMU02404
Gorilla gorilla gorilla	101130395		GORGO22569

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024