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adenosine A3 receptor

Summary

Gene Symbol

ADORA3

Organism

Homo sapiens (human)

External Links

NCBI Gene

140

PubChem

140

Alliance of Genome Resources

HGNC:268

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Palmitate
Reference proteome
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
H6VQ59
A0A0J9YWR0
P0DMS8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
response to wounding	TAS	9837869
regulation of heart contraction	TAS	9837869
negative regulation of cell migration	IMP	27886186
presynaptic modulation of chemical synaptic transmission	IEA
regulation of norepinephrine secretion	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

purinergic nucleotide receptor signaling pathway [inference]

G protein-coupled purinergic receptor signaling pathway [inference]

G protein-coupled adenosine receptor signaling pathway

G protein-coupled receptor signaling pathway [inference]

G protein-coupled purinergic receptor signaling pathway [inference]

G protein-coupled adenosine receptor signaling pathway

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

response to wounding

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

presynaptic modulation of chemical synaptic transmission

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

regulation of secretion by cell [inference]

regulation of catecholamine secretion [inference]

regulation of norepinephrine secretion

regulation of amine transport [inference]

regulation of catecholamine secretion [inference]

regulation of norepinephrine secretion

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

negative regulation of cell migration

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of biological process [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of cell motility [inference]

negative regulation of cell migration

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

purinergic nucleotide receptor signaling pathway [inference]

G protein-coupled purinergic receptor signaling pathway [inference]

G protein-coupled adenosine receptor signaling pathway

G protein-coupled receptor signaling pathway [inference]

G protein-coupled purinergic receptor signaling pathway [inference]

G protein-coupled adenosine receptor signaling pathway

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

presynaptic modulation of chemical synaptic transmission

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of cell motility [inference]

negative regulation of cell migration

regulation of secretion by cell [inference]

regulation of catecholamine secretion [inference]

regulation of norepinephrine secretion

regulation of cell motility [inference]

regulation of cell migration [inference]

negative regulation of cell migration

negative regulation of cell motility [inference]

negative regulation of cell migration

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of heart contraction

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of cyclase activity [inference]

positive regulation of adenylate cyclase activity [inference]

activation of adenylate cyclase activity

positive regulation of lyase activity [inference]

positive regulation of adenylate cyclase activity [inference]

activation of adenylate cyclase activity

regulation of catalytic activity [inference]

regulation of cyclase activity [inference]

positive regulation of cyclase activity [inference]

positive regulation of adenylate cyclase activity [inference]

activation of adenylate cyclase activity

regulation of adenylate cyclase activity [inference]

positive regulation of adenylate cyclase activity [inference]

activation of adenylate cyclase activity

positive regulation of catalytic activity [inference]

positive regulation of cyclase activity [inference]

positive regulation of adenylate cyclase activity [inference]

activation of adenylate cyclase activity

positive regulation of lyase activity [inference]

positive regulation of adenylate cyclase activity [inference]

activation of adenylate cyclase activity

regulation of lyase activity [inference]

regulation of adenylate cyclase activity [inference]

positive regulation of adenylate cyclase activity [inference]

activation of adenylate cyclase activity

positive regulation of lyase activity [inference]

positive regulation of adenylate cyclase activity [inference]

activation of adenylate cyclase activity

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

Displaying **all 5** entries
GO Term	Evidence Code	PMID
Schaffer collateral - CA1 synapse	IEA
plasma membrane	IBA TAS
dendrite	IBA
presynaptic membrane	IEA
synapse	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

presynaptic membrane

cell junction [inference]

synapse

Schaffer collateral - CA1 synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

Displaying 1 entry
GO Term	Evidence Code	PMID
G protein-coupled adenosine receptor activity	IBA

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled adenosine receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Cytosolic iron-sulfur protein assembly protein

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
iron-sulfur cluster assembly

Displaying **all 4** entries
InterPro
Probable cytosolic iron-sulfur protein assembly protein, CIAO1/Cia1
WD40 repeat
WD40-repeat-containing domain superfamily
WD40/YVTN repeat-like-containing domain superfamily

Ortholog

Displaying entries **51 - 60** of 67 in total

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Species	Gene ID	Orthologous MAtrix
Aotus nancymaae	105727939	AOTNA31086
Propithecus coquereli	105822079	PROCO30132
Dipodomys ordii	105991955	DIPOR14969
Mustela putorius furo	106003534	MUSPF05996
Equus asinus asinus	106828600	EQUAS14816
Rhinopithecus bieti	108528084	RHIBE00319
Crocodylus porosus	109317884	CROPO24124
Phascolarctos cinereus	110218719	PHACI20309
Myotis lucifugus	111826773	MYOLU07334
Vulpes vulpes	112907957	VULVU33628