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MIRAGE
SLIT-ROBO Rho GTPase activating protein 2
Summary
- Gene Symbol
-
- Srgap2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Cell membrane
- Cell projection
- Coiled coil
- Cytoplasm
- Cytoplasmic vesicle
- GTPase activation
- Methylation
- Neurogenesis
- Nucleus
- Phosphoprotein
- Postsynaptic cell membrane
- Reference proteome
- SH3 domain
- Proteins
| UniProt | Protein Name |
|---|---|
| Q91Z67 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| lamellipodium assembly involved in ameboidal cell migration |
|
|
| signal transduction | ||
| extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration | ||
| regulation of cell migration | ||
| negative regulation of cell migration |
GO Hierarchy
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| GTPase activator activity | ||
| GTPase activator activity | ||
| protein binding | ||
| small GTPase binding | ||
| small GTPase binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- slit-robo rho gtpase-activating
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| negative regulation of cell migration |
| InterPro |
|---|
| AH/BAR domain superfamily |
| F-BAR domain |
| FCH domain |
| Rho GTPase activation protein |
| Rho GTPase-activating protein domain |
| SH3 domain |
| SH3-like domain superfamily |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 393 | WB:WBGene00006406 | ||
| 9901 | WB:WBGene00006406 | ||
| 14270 | Xenbase:XB-GENE-5897849 | ||
| 23380 | Xenbase:XB-GENE-5897849 | HUMAN54446 | |
| 57522 | WB:WBGene00006406 | ||
| 117600 | WB:WBGene00006406 | ||
| 259302 | WB:WBGene00006406 | ||
| 360840 | RATNO06702 | ||
| 457680 | PANTR23512 | ||
| 478949 | CANLF14325 |
