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folate receptor beta

Summary

Gene Symbol

Folr2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

14276

PubChem

14276

Alliance of Genome Resources

MGI:95569

Annotation

Keyword

Cell membrane
Disulfide bond
Folate-binding
GPI-anchor
Receptor
Reference proteome
Signal
Transport

Proteins

Displaying 1 entry
UniProt	Protein Name
Q05685	Folate receptor 2 Folate-binding protein 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
post-translational protein targeting to endoplasmic reticulum membrane	TAS	11111049
cell adhesion	IBA
fusion of sperm to egg plasma membrane involved in single fertilization	IBA
positive regulation of cell population proliferation	IEA
folic acid transport	ISS

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to folic acid

cell adhesion

cell recognition [inference]

cell-cell recognition [inference]

sperm-egg recognition

cellular process involved in reproduction in multicellular organism [inference]

fusion of sperm to egg plasma membrane involved in single fertilization

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein targeting to membrane [inference]

post-translational protein targeting to endoplasmic reticulum membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to endoplasmic reticulum [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER [inference]

post-translational protein targeting to endoplasmic reticulum membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER [inference]

post-translational protein targeting to endoplasmic reticulum membrane

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to membrane [inference]

post-translational protein targeting to endoplasmic reticulum membrane

protein targeting to ER [inference]

post-translational protein targeting to endoplasmic reticulum membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER [inference]

post-translational protein targeting to endoplasmic reticulum membrane

establishment of protein localization to membrane [inference]

protein targeting to membrane [inference]

post-translational protein targeting to endoplasmic reticulum membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein targeting to membrane [inference]

post-translational protein targeting to endoplasmic reticulum membrane

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to folic acid

cellular response to chemical stimulus [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to folic acid

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to folic acid

cellular response to organonitrogen compound [inference]

cellular response to folic acid

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to folic acid

cellular response to oxygen-containing compound [inference]

cellular response to folic acid

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization [inference]

plasma membrane organization [inference]

plasma membrane fusion [inference]

fusion of sperm to egg plasma membrane involved in single fertilization

membrane fusion [inference]

plasma membrane fusion [inference]

fusion of sperm to egg plasma membrane involved in single fertilization

reproductive process [inference]

cellular process involved in reproduction in multicellular organism [inference]

fusion of sperm to egg plasma membrane involved in single fertilization

sperm-egg recognition

response to stimulus [inference]

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

response to nutrient [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to folic acid

response to vitamin [inference]

response to folic acid [inference]

cellular response to folic acid

cellular response to vitamin [inference]

cellular response to folic acid

cellular response to nutrient levels [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to folic acid

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to folic acid

cellular response to external stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to folic acid

response to endogenous stimulus [inference]

cellular response to endogenous stimulus [inference]

cellular response to organonitrogen compound [inference]

cellular response to folic acid

response to chemical [inference]

response to nutrient [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to folic acid

response to vitamin [inference]

response to folic acid [inference]

cellular response to folic acid

cellular response to vitamin [inference]

cellular response to folic acid

response to organic substance [inference]

response to organonitrogen compound [inference]

response to folic acid [inference]

cellular response to folic acid

cellular response to organonitrogen compound [inference]

cellular response to folic acid

response to organic cyclic compound [inference]

response to folic acid [inference]

cellular response to folic acid

cellular response to organic cyclic compound [inference]

cellular response to folic acid

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to folic acid

cellular response to organonitrogen compound [inference]

cellular response to folic acid

cellular response to chemical stimulus [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to folic acid

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to folic acid

cellular response to organonitrogen compound [inference]

cellular response to folic acid

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to folic acid

cellular response to oxygen-containing compound [inference]

cellular response to folic acid

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to folic acid [inference]

cellular response to folic acid

cellular response to organonitrogen compound [inference]

cellular response to folic acid

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to folic acid

response to oxygen-containing compound [inference]

response to folic acid [inference]

cellular response to folic acid

cellular response to oxygen-containing compound [inference]

cellular response to folic acid

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to folic acid

cellular response to chemical stimulus [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to folic acid

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to folic acid

cellular response to organonitrogen compound [inference]

cellular response to folic acid

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to folic acid

cellular response to oxygen-containing compound [inference]

cellular response to folic acid

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to endoplasmic reticulum [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER [inference]

post-translational protein targeting to endoplasmic reticulum membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER [inference]

post-translational protein targeting to endoplasmic reticulum membrane

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to membrane [inference]

post-translational protein targeting to endoplasmic reticulum membrane

protein targeting to ER [inference]

post-translational protein targeting to endoplasmic reticulum membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER [inference]

post-translational protein targeting to endoplasmic reticulum membrane

establishment of protein localization to membrane [inference]

protein targeting to membrane [inference]

post-translational protein targeting to endoplasmic reticulum membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein targeting to membrane [inference]

post-translational protein targeting to endoplasmic reticulum membrane

establishment of localization [inference]

transport [inference]

vitamin transport [inference]

folic acid transport

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

folic acid transport

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

folic acid transport

modified amino acid transport [inference]

folic acid transport

nitrogen compound transport [inference]

amide transport [inference]

folic acid transport

modified amino acid transport [inference]

folic acid transport

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to membrane [inference]

post-translational protein targeting to endoplasmic reticulum membrane

protein targeting to ER [inference]

post-translational protein targeting to endoplasmic reticulum membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER [inference]

post-translational protein targeting to endoplasmic reticulum membrane

establishment of protein localization to membrane [inference]

protein targeting to membrane [inference]

post-translational protein targeting to endoplasmic reticulum membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein targeting to membrane [inference]

post-translational protein targeting to endoplasmic reticulum membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to endoplasmic reticulum [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER [inference]

post-translational protein targeting to endoplasmic reticulum membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER [inference]

post-translational protein targeting to endoplasmic reticulum membrane

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to membrane [inference]

post-translational protein targeting to endoplasmic reticulum membrane

protein targeting to ER [inference]

post-translational protein targeting to endoplasmic reticulum membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER [inference]

post-translational protein targeting to endoplasmic reticulum membrane

establishment of protein localization to membrane [inference]

protein targeting to membrane [inference]

post-translational protein targeting to endoplasmic reticulum membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein targeting to membrane [inference]

post-translational protein targeting to endoplasmic reticulum membrane

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

Displaying **all 4** entries
GO Term	Evidence Code	PMID
external side of plasma membrane	ISS
external side of plasma membrane	ISO
external side of plasma membrane	IBA
cell surface	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell surface

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
folic acid binding	ISS
folic acid binding	ISO
folic acid binding	TAS	11111049
signaling receptor activity	IBA
folic acid receptor activity	ISS

GO Hierarchy

molecular function

binding [inference]

amide binding [inference]

folic acid binding

small molecule binding [inference]

vitamin binding [inference]

folic acid binding

organic acid binding [inference]

carboxylic acid binding [inference]

folic acid binding

heterocyclic compound binding [inference]

folic acid binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

folic acid binding

modified amino acid binding [inference]

folic acid binding

organic cyclic compound binding [inference]

folic acid binding

cargo receptor activity [inference]

folic acid receptor activity

molecular transducer activity [inference]

signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Folate receptor

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
fusion of sperm to egg plasma membrane involved in single fertilization
sperm-egg recognition

Displaying **all 2** entries
InterPro
Folate receptor-like
Folate receptor

Ortholog

Displaying entries **1 - 10** of 61 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	2348	Xenbase:XB-GENE-948101
Homo sapiens	2350	Xenbase:XB-GENE-948101	HUMAN07967
Homo sapiens	2352	Xenbase:XB-GENE-948101	HUMAN07954
Xenopus tropicalis	14275	Xenbase:XB-GENE-948101
Xenopus tropicalis	14276	Xenbase:XB-GENE-948101
Xenopus tropicalis	64931	Xenbase:XB-GENE-948101
Rattus norvegicus	293154		RATNO20831
Xenopus tropicalis	390243	Xenbase:XB-GENE-948101
Sus scrofa	396853		PIGXX34932
Canis lupus familiaris	476816		CANLF08306

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Acknowledgements