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formyl peptide receptor 1

Summary

Gene Symbol

Fpr1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

14293

PubChem

14293

Alliance of Genome Resources

MGI:107443

Annotation

Keyword

Cell membrane
Chemotaxis
Disulfide bond
G-protein coupled receptor
Glycoprotein
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P33766	N-formyl peptide receptor N-formylpeptide chemoattractant receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
complement receptor mediated signaling pathway	IBA
chemotaxis	TAS	12470609
inflammatory response	IBA
G protein-coupled receptor signaling pathway	IDA	12470609
phospholipase C-activating G protein-coupled receptor signaling pathway	ISO

GO Hierarchy

biological process

immune system process [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

locomotion [inference]

taxis [inference]

chemotaxis

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

regulation of response to stimulus [inference]

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cytoplasm	ISO
cytoplasm	IEA
plasma membrane	ISO
plasma membrane	IBA
plasma membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
G protein-coupled receptor binding	ISO
G protein-coupled receptor binding	IEA
complement receptor activity	IBA
G protein-coupled receptor activity	ISO
N-formyl peptide receptor activity	ISO	12218158

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

N-formyl peptide receptor activity

transmembrane signaling receptor activity [inference]

complement receptor activity

G protein-coupled receptor activity

G protein-coupled peptide receptor activity [inference]

N-formyl peptide receptor activity

immune receptor activity [inference]

complement receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

G-protein coupled

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
inflammatory response
phospholipase C-activating G protein-coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration

Displaying **all 3** entries
InterPro
Formyl peptide receptor-related
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Ortholog

Displaying entries **1 - 10** of 36 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	1240	ZFIN:ZDB-GENE-121227-2
Homo sapiens	2357	ZFIN:ZDB-GENE-121227-2	HUMAN45551
Danio rerio	2358	ZFIN:ZDB-GENE-131127-346
Danio rerio	2359	ZFIN:ZDB-GENE-131127-346
Danio rerio	2854	ZFIN:ZDB-GENE-131121-596
Danio rerio	14289	ZFIN:ZDB-GENE-141212-254
Danio rerio	14290	ZFIN:ZDB-GENE-141212-254
Danio rerio	14291	ZFIN:ZDB-GENE-141212-254
Danio rerio	14293	ZFIN:ZDB-GENE-141212-254
Danio rerio	14294	ZFIN:ZDB-GENE-141212-254