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eukaryotic translation initiation factor 5A like 1

Summary

Gene Symbol

EIF5AL1

Organism

Homo sapiens (human)

External Links

NCBI Gene

143244

PubChem

143244

Alliance of Genome Resources

HGNC:17419

Annotation

Keyword

Cytoplasm
Elongation factor
Endoplasmic reticulum
Hypusine
Membrane
Nucleus
Proteomics identification
RNA-binding
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6IS14	Eukaryotic initiation factor 5A isoform 1-like

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
positive regulation of translational termination	IEA
positive regulation of translational elongation	IEA
translational elongation	IBA

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translational elongation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translational elongation

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translational elongation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

translational elongation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translational elongation

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translational elongation

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

regulation of translational elongation [inference]

positive regulation of translational elongation

regulation of translational termination [inference]

positive regulation of translational termination

positive regulation of translation [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of protein metabolic process [inference]

positive regulation of translation [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of amide metabolic process [inference]

positive regulation of translation [inference]

positive regulation of protein metabolic process [inference]

positive regulation of translation [inference]

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

regulation of translational elongation [inference]

positive regulation of translational elongation

regulation of translational termination [inference]

positive regulation of translational termination

positive regulation of translation [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

regulation of nitrogen compound metabolic process [inference]

regulation of amide metabolic process [inference]

regulation of translation [inference]

regulation of translational elongation [inference]

positive regulation of translational elongation

regulation of translational termination [inference]

positive regulation of translational termination

positive regulation of translation [inference]

positive regulation of amide metabolic process [inference]

positive regulation of translation [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of amide metabolic process [inference]

positive regulation of translation [inference]

positive regulation of protein metabolic process [inference]

positive regulation of translation [inference]

regulation of protein metabolic process [inference]

regulation of translation [inference]

regulation of translational elongation [inference]

positive regulation of translational elongation

regulation of translational termination [inference]

positive regulation of translational termination

positive regulation of translation [inference]

positive regulation of protein metabolic process [inference]

positive regulation of translation [inference]

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

regulation of translational elongation [inference]

positive regulation of translational elongation

regulation of translational termination [inference]

positive regulation of translational termination

positive regulation of translation [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of protein metabolic process [inference]

positive regulation of translation [inference]

regulation of protein metabolic process [inference]

regulation of translation [inference]

regulation of translational elongation [inference]

positive regulation of translational elongation

regulation of translational termination [inference]

positive regulation of translational termination

positive regulation of translation [inference]

positive regulation of protein metabolic process [inference]

positive regulation of translation [inference]

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of translation [inference]

regulation of translational elongation [inference]

positive regulation of translational elongation

regulation of translational termination [inference]

positive regulation of translational termination

positive regulation of translation [inference]

positive regulation of protein metabolic process [inference]

positive regulation of translation [inference]

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of protein metabolic process [inference]

positive regulation of translation [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of amide metabolic process [inference]

positive regulation of translation [inference]

positive regulation of protein metabolic process [inference]

positive regulation of translation [inference]

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex disassembly [inference]

positive regulation of translational termination

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

regulation of translational elongation [inference]

positive regulation of translational elongation

regulation of translational termination [inference]

positive regulation of translational termination

positive regulation of translation [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex disassembly [inference]

positive regulation of translational termination

regulation of cellular component organization [inference]

regulation of protein-containing complex disassembly [inference]

regulation of translational termination [inference]

positive regulation of translational termination

positive regulation of protein-containing complex disassembly [inference]

positive regulation of translational termination

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex disassembly [inference]

positive regulation of translational termination

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA
nucleus	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 3** entries
GO Term	Evidence Code	PMID
ribosome binding	IEA
RNA binding	IEA
translation elongation factor activity	IBA

GO Hierarchy

molecular function

binding [inference]

protein-containing complex binding [inference]

ribonucleoprotein complex binding [inference]

ribosome binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

translation regulator activity, nucleic acid binding [inference]

translation factor activity, RNA binding [inference]

translation elongation factor activity

translation regulator activity [inference]

translation regulator activity, nucleic acid binding [inference]

translation factor activity, RNA binding [inference]

translation elongation factor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Eukaryotic translation initiation factor 5a

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
positive regulation of translational elongation
positive regulation of translational termination

Displaying **all 7** entries
InterPro
Large ribosomal subunit protein uL2, domain 2
Nucleic acid-binding, OB-fold
Translation elongation factor IF5A-like
Translation elongation factor, IF5A C-terminal
Translation elongation factor, IF5A, hypusine site
Translation initiation factor 5A-like, N-terminal
Translation protein SH3-like domain superfamily

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:3498	pancreatic ductal adenocarcinoma	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 15 in total

1

2

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Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	37846		FB:FBgn0285952
Caenorhabditis elegans	174367		WB:WBGene00002065
Mus musculus	276770		MGI:106248
Rattus norvegicus	287444		RGD:1308029
Danio rerio	406464		ZFIN:ZDB-GENE-040426-2229
Xenopus tropicalis	448142		Xenbase:XB-GENE-998075
Pan troglodytes	742986	9598_0:002c00
Saccharomyces cerevisiae S288C	853506		SGD:S000003808
Saccharomyces cerevisiae S288C	856677		SGD:S000000760
Pongo abelii	100457535	9601_0:00419c

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Last updated: December 9, 2024