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fucosyltransferase 2

Summary

Gene Symbol

Fut2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

14344

KEGG Gene ID

mmu:14344

PubChem

14344

Alliance of Genome Resources

MGI:109374

Annotation

Keyword

Glycoprotein
Glycosyltransferase
Golgi apparatus
Lipid metabolism
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9JL27	Alpha(1,2)FT 2 Fucosyltransferase 2 GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2 GDP-fucose: beta-galactoside alpha1,2-fucosyltransferase Secretory blood group protein 2 Type 1 galactoside alpha-(1,2)-fucosyltransferase FUT2 Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT2
A6H6C9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 8** of 8 in total

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GO Term	Evidence Code	PMID
carbohydrate metabolic process
glycolipid metabolic process	IMP	14967068
lipid metabolic process

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

biosynthetic process [inference]

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process

primary metabolic process [inference]

carbohydrate metabolic process

oligosaccharide metabolic process [inference]

oligosaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

lipid metabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

glycosylation [inference]

fucosylation

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

carbohydrate metabolic process

oligosaccharide metabolic process [inference]

oligosaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

lipid metabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

carbohydrate derivative metabolic process [inference]

liposaccharide metabolic process [inference]

glycolipid metabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of cell adhesion

regulation of cell population proliferation [inference]

regulation of epithelial cell proliferation [inference]

regulation of endothelial cell proliferation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
Golgi apparatus	ISO	30401457
Golgi cisterna membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

Golgi cisterna membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying **all 3** entries
GO Term	Evidence Code	PMID
galactoside 2-alpha-L-fucosyltransferase activity	IBA IDA IMP ISO	11323419 24062455
alpha-(1,2)-fucosyltransferase activity	IDA IMP ISO	11018479 11368156 11713270 14967068
fucosyltransferase activity	IDA	11018479

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

fucosyltransferase activity

alpha-(1,2)-fucosyltransferase activity

galactoside 2-alpha-L-fucosyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

galactoside 2-alpha-L-fucosyltransferase 2

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
fucosylation
fucosyltransferase activity
galactoside 2-alpha-L-fucosyltransferase activity
lipid metabolic process
transferase activity

Displaying 1 entry
InterPro
Glycosyl transferase, family 11

KEGG BRITE Database

Orthology

K00718

Name

galactoside 2-L-fucosyltransferase 1/2 [EC:2.4.1.69]

References

Reactions

Displaying entries **1 - 10** of 12 in total

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KEGG Reaction	Enzyme	Acceptor	Product
R06086	2.4.1.69	G98900YM	G87164WU
R06156	2.4.1.69	G00049MO	G00050MO
R06170	2.4.1.69	G56390QA	G63238VS
R06089	2.4.1.69	G98726UE	G28261RX
R05968	2.4.1.69	G99053DY	G98465JN
R06027	2.4.1.-	G60645OK	G77593JU
R06090	2.4.1.69	G28261RX	G87164WU
R06024	2.4.1.69	G58896AZ	G13636IT
R06035	2.4.1.69	G84034JH	G66427ZQ
R06031	2.4.1.69	G64885AH	G58990QD

Rhea

RHEA:50664

a β-D-galactosyl-(1→3)-N-acetyl-β-D-glucosaminyl derivative + GDP-β-L-fucose

an α-L-Fuc-(1→2)-β-D-Gal-(1→3)-β-D-GlcNAc derivative + H⁺ + GDP

Enzyme

2.4.1.69

PMID

RHEA:32175

a β-D-Gal-(1→3)-β-D-GlcNAc-(1→3)-β-D-Gal-(1→4)-β-D-Glc-(1↔1ʼ)-Cer(d18:1(4E)) + GDP-β-L-fucose

H⁺ + α-L-fucosyl-(1→2)- β-D-galactosyl-(1→3)-N-acetyl-β-D-glucosaminyl-(1→3)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1ʼ)-N-acylsphing-4-enine + GDP

Enzyme

2.4.1.69

PMID

RHEA:50668

a β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl derivative + GDP-β-L-fucose

an α-L-Fuc-(1→2)-β-D-Gal-(1→4)-β-D-GlcNAc derivative + H⁺ + GDP

Enzyme

2.4.1.344

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050731	vitamin B12 deficiency	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP002490
Gene Name: fucosyltransferase 2

Ortholog

Displaying entries **31 - 40** of **117** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Ictidomys tridecemlineatus	101974321	43179_0:00517f
Ictidomys tridecemlineatus	101974597		ICTTR05975
Microtus ochrogaster	101985385	79684_0:003ea5
Microtus ochrogaster	102001037	79684_0:003e87
Chinchilla lanigera	102006080	34839_0:004b17
Chinchilla lanigera	102006400	34839_0:004aec
Capra hircus	102185028		CAPHI09365
Myotis lucifugus	102425138		MYOLU19681
Myotis lucifugus	102433448		MYOLU17445
Peromyscus maniculatus bairdii	102907953	230844_0:00035f

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements