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MIRAGE
colony stimulating factor 1
Summary
- Gene Symbol
-
- CSF1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Cytokine
- Direct protein sequencing
- Disulfide bond
- Growth factor
- Inflammatory response
- Innate immunity
- Phosphoprotein
- Proteoglycan
- Reference proteome
- Secreted
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P09603 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of gene expression | ||
| regulation of macrophage derived foam cell differentiation | ||
| positive regulation of macrophage derived foam cell differentiation | ||
| positive regulation of macrophage chemotaxis | ||
| monocyte differentiation |
GO Hierarchy
biological process
cellular process [inference]
multicellular organismal process [inference]
developmental process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of signaling [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cell differentiation [inference]
positive regulation of developmental process [inference]
regulation of multicellular organismal development [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| extracellular space | ||
| endoplasmic reticulum lumen | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytokine activity | ||
| cytokine activity | ||
| macrophage colony-stimulating factor receptor binding | ||
| macrophage colony-stimulating factor receptor binding | ||
| protein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- macrophage colony-stimulating factor 1
- Functional Category
-
- E: Amino acid transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cytokine activity |
| growth factor activity |
| osteoclast differentiation |
| positive regulation of macrophage differentiation |
| InterPro |
|---|
| Four-helical cytokine-like, core |
| Macrophage colony stimulating factor-1 |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:13949 | interstitial cystitis |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 1435 | Xenbase:XB-GENE-22041694 | ||
| 12977 | ZFIN:ZDB-GENE-061215-106 | MOUSE38962 | |
| 78965 | RATNO25389 | ||
| 281094 | BOVIN26318 | ||
| 457127 | PANTR22089 | ||
| 611795 | CANLF16818 | ||
| 702532 | MACMU22262 | ||
| 100146493 | HORSE33587 | ||
| 100338577 | RABIT03603 | ||
| 100386071 | CALJA41956 |
