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colony stimulating factor 2 receptor subunit alpha

Summary

Gene Symbol

CSF2RA

Organism

Homo sapiens (human)

External Links

NCBI Gene

1438

PubChem

1438

Alliance of Genome Resources

HGNC:2435

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Disease variant
Disulfide bond
Glycoprotein
Receptor
Reference proteome
Secreted
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P15509	CDw116

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
receptor signaling pathway via JAK-STAT	IDA	18692472
positive regulation of cell population proliferation	IBA
cytokine-mediated signaling pathway	IBA
granulocyte-macrophage colony-stimulating factor signaling pathway	IDA	18692472
positive regulation of receptor signaling pathway via JAK-STAT	IBA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

growth hormone receptor signaling pathway

cytokine-mediated signaling pathway

granulocyte-macrophage colony-stimulating factor signaling pathway

receptor signaling pathway via STAT [inference]

receptor signaling pathway via JAK-STAT

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of leukocyte proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

growth hormone receptor signaling pathway

cytokine-mediated signaling pathway

granulocyte-macrophage colony-stimulating factor signaling pathway

receptor signaling pathway via STAT [inference]

receptor signaling pathway via JAK-STAT

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of leukocyte proliferation

regulation of leukocyte proliferation [inference]

positive regulation of leukocyte proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of leukocyte proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
extracellular region	IEA
cytosol	IBA
plasma membrane	NAS	1702217
plasma membrane	TAS
external side of plasma membrane	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

growth hormone receptor complex

plasma membrane signaling receptor complex [inference]

granulocyte macrophage colony-stimulating factor receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

granulocyte macrophage colony-stimulating factor receptor complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
cytokine receptor activity
growth hormone receptor activity	IBA
protein binding	IPI	25416956
peptide hormone binding	IBA
cytokine binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

cytokine binding

amide binding [inference]

peptide binding [inference]

peptide hormone binding

hormone binding [inference]

peptide hormone binding

molecular transducer activity [inference]

signaling receptor activity

transmembrane signaling receptor activity [inference]

cytokine receptor activity

growth hormone receptor activity

immune receptor activity [inference]

cytokine receptor activity

growth hormone receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:12120	pulmonary alveolar proteinosis	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 17 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Rattus norvegicus	1438	RGD:1594330
Mus musculus	12982	RGD:1594330	MOUSE25327
Canis lupus familiaris	609266		CANLF19510
Rattus norvegicus	652957		RATNO08791
Callithrix jacchus	100413917		CALJA47466
Pongo abelii	100452320		PONAB00293
Nomascus leucogenys	100596513		NOMLE39972
Nomascus leucogenys	100605652		NOMLE39972
Sus scrofa	100620339		PIGXX38935
Ovis aries	101115509		SHEEP19458