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colony stimulating factor 2 receptor subunit alpha

Summary

Gene Symbol

CSF2RA

Organism

Homo sapiens (human)

External Links

NCBI Gene

1438

PubChem

1438

Alliance of Genome Resources

HGNC:2435

JoGo

CSF2RA

TogoVar

CSF2RA

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Disease variant
Disulfide bond
Glycoprotein
Proteomics identification
Receptor
Reference proteome
Secreted
Signal
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0ABB0MVN9
A0ABB0MVP0
P15509	CDw116

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
receptor signaling pathway via JAK-STAT	IDA	18692472
positive regulation of cell population proliferation	IBA
cytokine-mediated signaling pathway	IBA
granulocyte-macrophage colony-stimulating factor signaling pathway	IDA	18692472
positive regulation of receptor signaling pathway via JAK-STAT	IBA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

growth hormone receptor signaling pathway

cytokine-mediated signaling pathway

granulocyte-macrophage colony-stimulating factor signaling pathway

receptor signaling pathway via STAT [inference]

receptor signaling pathway via JAK-STAT

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of leukocyte proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

growth hormone receptor signaling pathway

cytokine-mediated signaling pathway

granulocyte-macrophage colony-stimulating factor signaling pathway

receptor signaling pathway via STAT [inference]

receptor signaling pathway via JAK-STAT

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of leukocyte proliferation

regulation of leukocyte proliferation [inference]

positive regulation of leukocyte proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of leukocyte proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
extracellular region	IEA
cytosol	IBA
plasma membrane	NAS	1702217
plasma membrane	TAS
external side of plasma membrane	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

growth hormone receptor complex

plasma membrane signaling receptor complex [inference]

granulocyte macrophage colony-stimulating factor receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

granulocyte macrophage colony-stimulating factor receptor complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
cytokine receptor activity
growth hormone receptor activity	IBA
protein binding	IPI	25416956
peptide hormone binding	IBA
cytokine binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

cytokine binding

amide binding [inference]

peptide binding [inference]

peptide hormone binding

hormone binding [inference]

peptide hormone binding

molecular transducer activity [inference]

signaling receptor activity

transmembrane signaling receptor activity [inference]

cytokine receptor activity

growth hormone receptor activity

immune receptor activity [inference]

cytokine receptor activity

growth hormone receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

granulocyte-macrophage colony-stimulating factor receptor subunit alpha

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
cytokine-mediated signaling pathway

Displaying **all 4** entries
InterPro
Fibronectin type III superfamily
Immunoglobulin-like fold
Short hematopoietin receptor, family 2, conserved site
Type I cytokine receptor, cytokine-binding domain