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glucosidase, alpha, acid

Summary

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

14387

PubChem

14387

Alliance of Genome Resources

MGI:95609

Annotation

Keyword

Direct protein sequencing
Disulfide bond
Glycoprotein
Glycosidase
Lysosome
Membrane
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
P70699	Acid maltase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 25 in total

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GO Term	Evidence Code	PMID
regulation of the force of heart contraction	IMP	11328962
diaphragm contraction	ISO
diaphragm contraction	IMP	15169761
heart morphogenesis	IMP	9384603
glycogen metabolic process	IMP	10547605 11590121 12115977 15169761 15207257 9384603 9668092

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

macroautophagy [inference]

glycophagy

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

carbohydrate catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process

glycogen catabolic process

cellular catabolic process [inference]

autophagy [inference]

macroautophagy [inference]

glycophagy

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

glucan metabolic process [inference]

glycogen metabolic process

glycogen catabolic process

glucan catabolic process [inference]

glycogen catabolic process

carbohydrate catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

glucan metabolic process [inference]

glycogen metabolic process

glycogen catabolic process

glucan catabolic process [inference]

glycogen catabolic process

carbohydrate catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

glucan metabolic process [inference]

glycogen metabolic process

glycogen catabolic process

glucan catabolic process [inference]

glycogen catabolic process

macromolecule catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

carbohydrate catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

cellular process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process

glycogen catabolic process

cellular catabolic process [inference]

autophagy [inference]

macroautophagy [inference]

glycophagy

maintenance of location in cell [inference]

vacuolar sequestering

process utilizing autophagic mechanism [inference]

autophagy [inference]

macroautophagy [inference]

glycophagy

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vacuole organization [inference]

lytic vacuole organization [inference]

lysosome organization

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

muscle contraction [inference]

striated muscle contraction

skeletal muscle contraction [inference]

involuntary skeletal muscle contraction [inference]

diaphragm contraction

cardiac muscle contraction

respiratory system process [inference]

diaphragm contraction

nervous system process [inference]

neuromuscular process [inference]

behavior [inference]

locomotory behavior

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

heart morphogenesis

anatomical structure development [inference]

blood vessel development [inference]

artery development [inference]

aorta development

tissue development

homeostatic process [inference]

cellular homeostasis [inference]

muscle cell cellular homeostasis

localization [inference]

maintenance of location [inference]

maintenance of location in cell [inference]

vacuolar sequestering

biological regulation [inference]

regulation of biological process [inference]

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of heart contraction [inference]

regulation of the force of heart contraction

regulation of biological quality [inference]

regulation of the force of heart contraction

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GO Term	Evidence Code	PMID
lysosome	ISO
lysosome	TAS	11785984
lysosome	IMP	15207257
lysosomal membrane	IEA
membrane	IMP	20080761

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen [inference]

autolysosome lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle

vacuole [inference]

lytic vacuole [inference]

lysosome

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GO Term	Evidence Code	PMID
alpha-1,4-glucosidase activity	ISO	24417
alpha-1,4-glucosidase activity	IDA	7323947
alpha-1,4-glucosidase activity	IMP	11328962 11590121 11785984 15169761 9384603 9668092
alpha-1,4-glucosidase activity	IBA
carbohydrate binding	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

glucosidase activity [inference]

glucan 1,6-alpha-glucosidase activity

alpha-glucosidase activity

alpha-1,4-glucosidase activity

binding [inference]

carbohydrate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

lysosomal alpha-glucosidase

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
alpha-glucosidase activity
catalytic activity
glycogen catabolic process
hydrolase activity, acting on glycosyl bonds
hydrolase activity
lysosome organization

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InterPro
Galactose mutarotase-like domain superfamily
Glycoside hydrolase family 31, N-terminal domain
Glycoside hydrolase family 31, TIM barrel domain
Glycoside hydrolase superfamily
Glycosyl hydrolase family 31, C-terminal domain
Glycosyl hydrolase, all-beta
Glycosyl hydrolases family 31, active site
Glycosyl hydrolases family 31, conserved site
P-type trefoil domain superfamily
P-type trefoil domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:2752	glycogen storage disease II	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	2548	Xenbase:XB-GENE-6054131	HUMAN36786
Caenorhabditis elegans	6476	WB:WBGene00019895
Caenorhabditis elegans	8972	WB:WBGene00019895
Xenopus tropicalis	14387	Xenbase:XB-GENE-6054131
Caenorhabditis elegans	69983	WB:WBGene00019895
Caenorhabditis elegans	93432	WB:WBGene00019895
Caenorhabditis elegans	232714	WB:WBGene00019895
Bos taurus	280798		BOVIN13836
Rattus norvegicus	367562	Xenbase:XB-GENE-6054131	RATNO03032
Pan troglodytes	454940		PANTR15614