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Guidelines

MIRAGE

beta 3-glucosyltransferase

Summary

Gene Symbol

B3GLCT

Aliases

B3GTL
B3Glc-T
beta-1,3-glucosyltransferase

Organism

Homo sapiens (human)

External Links

NCBI Gene

145173

GGDB ID

gg184

HGNC

20207

mRNA

NM_194318

map

13q12.3

Protein

NP_919299

OMIM

610308

KEGG Gene ID

hsa:145173

PubChem

145173

Alliance of Genome Resources

HGNC:20207

Annotation

Keyword

Congenital disorder of glycosylation
Dwarfism
Endoplasmic reticulum
Fucose metabolism
Glycoprotein
Glycosyltransferase
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6Y288	Beta 3-glucosyltransferase Beta-3-glycosyltransferase-like

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
skeletal system development	IEA
fucose metabolic process	IEA
brain development	IEA
protein secretion	IEA
gene expression	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process

glycosylation [inference]

fucosylation [inference]

protein O-linked fucosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cilium organization [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

plasma membrane bounded cell projection organization [inference]

cilium organization [inference]

cilium assembly

plasma membrane bounded cell projection assembly [inference]

cilium assembly

export from cell [inference]

secretion by cell [inference]

protein secretion

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

brain development

sensory organ development [inference]

eye development [inference]

camera-type eye development

system development [inference]

skeletal system development

appendage development [inference]

limb development

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

establishment of localization [inference]

transport [inference]

secretion [inference]

secretion by cell [inference]

protein secretion

organic substance transport [inference]

protein transport [inference]

protein secretion

nitrogen compound transport [inference]

protein transport [inference]

protein secretion

export from cell [inference]

secretion by cell [inference]

protein secretion

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
acetylglucosaminyltransferase activity	IBA
glycosyltransferase activity	TAS

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

beta 3-glucosyltransferase

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
acetylglucosaminyltransferase activity

Displaying 1 entry
InterPro
Protein of unknown function DUF604

GlycoGene Database (GGDB)

GGDB ID

gg184

Gene Symbol

B3GLCT

Reactions

Displaying 1 entry
Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
UDP-Glc	G96881BQ	[alpha]-pNp	G36855WW	[alpha]-pNp	16899492

Displaying **all 4** entries
Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
UDP-Glc	G96881BQ	[alpha]-pNp	G36855WW	[alpha]-pNp	16899492
UDP-Glc	G61459JW	[beta]-pNp	G70899NZ	[beta]-pNp	16899492
UDP-Glc	G39023AU	[beta]-pNp	G71649FF	[beta]-pNp	16899492
UDP-Glc	G96881BQ	rat F-spondin TSR4	G36855WW	rat F-spondin TSR4	17032646

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Donor	Acceptor	Reducing terminal(Acceptor)	Reference
UDP-Gal	G96881BQ	TSR4	17032646
UDP-GalNAc	G96881BQ	TSR4	17032646
UDP-Glc	G58161NS	[alpha]-pNp	16899492
UDP-Glc	G65889KE	[alpha]-o-nitrophenol	16899492
UDP-Glc	G96881BQ	[beta]-pNp	16899492

Orthologous Gene

Displaying 1 entry
Species	Protein	mRNA
Mus musculus	NP_001074673	NM_001081204

KEGG BRITE Database

Orthology

K13675

Name

UDP-glucose:O-linked fucose beta-1,3-glucosyltransferase [EC:2.4.1.-]

References

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0080201	Peters plus syndrome	Glyco-Disease Genes Database Alliance of Genome Resources

The Human Phenotype Ontology

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HPO ID	HPO Term
HP:0000003	Multicystic kidney dysplasia
HP:0000007	Autosomal recessive inheritance
HP:0000013	Hypoplasia of the uterus
HP:0000023	Inguinal hernia
HP:0000028	Cryptorchidism
HP:0000047	Hypospadias
HP:0000059	Hypoplastic labia majora
HP:0000060	Clitoral hypoplasia
HP:0000073	Ureteral duplication
HP:0000075	Renal duplication

Displaying **all 2** entries
Disease ID	Disease Name
OMIM:261540	Peters plus syndrome
ORPHA:709	Peters plus syndrome

PubChem Disease

GHR Health Conditions

Peters plus syndrome

MedGen Diseases

Peters plus syndrome

OMIM Phenotypes

PETERS-PLUS SYNDROME; PTRPLS

KEGG Diseases

Peters anomaly

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

Ortholog

Displaying entries **1 - 10** of 58 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	33844	Xenbase:XB-GENE-951583
Xenopus tropicalis	145173	Xenbase:XB-GENE-951583
Xenopus tropicalis	178968	Xenbase:XB-GENE-951583
Mus musculus	381694	Xenbase:XB-GENE-951583	MOUSE44600
Pan troglodytes	452523		PANTR07545
Xenopus tropicalis	564156	Xenbase:XB-GENE-951583
Rattus norvegicus	689765	Xenbase:XB-GENE-951583	RATNO06095
Macaca mulatta	713498		MACMU16690
Xenopus tropicalis	780006	Xenbase:XB-GENE-951583
Danio rerio	799443	Xenbase:XB-GENE-951583	DANRE08282

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.2.1

Last updated: April 7, 2025