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MIRAGE
growth differentiation factor 5
Summary
- Gene Symbol
-
- Gdf5
- Organism
- Mus musculus (house mouse)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| chondrocyte differentiation | ||
| transmembrane receptor protein serine/threonine kinase signaling pathway | ||
| response to mechanical stimulus | ||
| embryonic limb morphogenesis | ||
| BMP signaling pathway |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular space | ||
| extracellular space | ||
| plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| signaling receptor binding | ||
| cytokine activity | ||
| cytokine activity | ||
| protein binding | ||
| growth factor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- bone morphogenetic protein
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cytokine activity |
| growth factor activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050790 | fibular hypoplasia and complex brachydactyly | |
| DOID:0050794 | multiple synostoses syndrome | |
| DOID:0080051 | acromesomelic dysplasia, Hunter-Thompson type | |
| DOID:0080052 | acromesomelic dysplasia, Grebe type | |
| DOID:0110965 | brachydactyly type A2 | |
| DOID:0110970 | brachydactyly type C | |
| DOID:0110977 | brachydactyly type A1C | |
| DOID:8398 | osteoarthritis |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 8200 | Xenbase:XB-GENE-481784 | HUMAN56694 | |
| 14563 | Xenbase:XB-GENE-481784 | ||
| 252835 | RATNO28841 | ||
| 458202 | PANTR24729 | ||
| 485850 | CANLF09489 | ||
| 539559 | BOVIN05163 | ||
| 705432 | MACMU02631 | ||
| 100028734 | MONDO07007 | ||
| 100034228 | HORSE21604 | ||
| 100137480 | PAPAN12565 |
