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guanine nucleotide binding protein (G protein), beta 1

Summary

Gene Symbol

Gnb1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

14688

PubChem

14688

Alliance of Genome Resources

MGI:95781

Annotation

Keyword

3D-structure
Acetylation
Coiled coil
Direct protein sequencing
Phosphoprotein
Reference proteome
Repeat
Transducer
WD repeat

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P62874	Transducin beta chain 1
Q3TQ70	Transducin beta chain 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
G protein-coupled receptor signaling pathway	ISO
G protein-coupled receptor signaling pathway	TAS	1543505
G protein-coupled receptor signaling pathway	IDA	14712229
G protein-coupled receptor signaling pathway	IBA
phospholipase C-activating G protein-coupled receptor signaling pathway	IDA	10570481

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

phototransduction [inference]

phototransduction, visible light

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

muscle cell apoptotic process [inference]

striated muscle cell apoptotic process [inference]

cardiac muscle cell apoptotic process

cell population proliferation

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to hypoxia

cellular response to chemical stimulus [inference]

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of chemical stimulus [inference]

sensory perception of taste

developmental process [inference]

anatomical structure development [inference]

retina development in camera-type eye

response to stimulus [inference]

response to stress [inference]

response to hypoxia [inference]

cellular response to hypoxia

cellular response to stress [inference]

cellular response to hypoxia

response to external stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus [inference]

phototransduction [inference]

phototransduction, visible light

detection of visible light [inference]

phototransduction, visible light

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

detection of light stimulus [inference]

phototransduction [inference]

phototransduction, visible light

detection of visible light [inference]

phototransduction, visible light

detection of abiotic stimulus [inference]

detection of light stimulus [inference]

phototransduction [inference]

phototransduction, visible light

detection of visible light [inference]

phototransduction, visible light

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia [inference]

cellular response to hypoxia

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

response to chemical [inference]

cellular response to chemical stimulus [inference]

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

detection of stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus [inference]

phototransduction [inference]

phototransduction, visible light

detection of visible light [inference]

phototransduction, visible light

detection of abiotic stimulus [inference]

detection of light stimulus [inference]

phototransduction [inference]

phototransduction, visible light

detection of visible light [inference]

phototransduction, visible light

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to hypoxia

cellular response to chemical stimulus [inference]

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

phototransduction [inference]

phototransduction, visible light

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
photoreceptor outer segment	IDA	18367617
photoreceptor inner segment	ISO
cytoplasm	IBA
heterotrimeric G-protein complex	ISO	1543505 21812758
heterotrimeric G-protein complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

heterotrimeric G-protein complex

catalytic complex [inference]

GTPase complex [inference]

heterotrimeric G-protein complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

ciliary membrane [inference]

photoreceptor outer segment membrane

plasma membrane region [inference]

cell projection membrane [inference]

ciliary membrane [inference]

photoreceptor outer segment membrane

cell junction [inference]

synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
GTPase activity	ISO	1543505
signaling receptor complex adaptor activity	IBA
spectrin binding	ISO	23704327
protein-containing complex binding	ISO	23209302
alkylglycerophosphoethanolamine phosphodiesterase activity	ISO	21812758

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphoric diester hydrolase activity [inference]

alkylglycerophosphoethanolamine phosphodiesterase activity

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

GTPase activity

binding [inference]

protein binding [inference]

cytoskeletal protein binding [inference]

spectrin binding

enzyme binding [inference]

GTPase binding

protein-containing complex binding

spectrin binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

signaling adaptor activity [inference]

signaling receptor complex adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

guanine nucleotide-binding subunit beta

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
signaling receptor complex adaptor activity

Displaying **all 7** entries
InterPro
G-protein beta WD-40 repeat
G-protein, beta subunit
Guanine nucleotide-binding protein, beta subunit
WD40 repeat, conserved site
WD40 repeat
WD40-repeat-containing domain superfamily
WD40/YVTN repeat-like-containing domain superfamily

Ortholog

Displaying entries **1 - 10** of **109** in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	2782	Xenbase:XB-GENE-6076380	HUMAN46932
Xenopus tropicalis	14688	Xenbase:XB-GENE-6076380
Rattus norvegicus	24400		RATNO33059
Saccharomyces cerevisiae S288C	59345	SGD:S000005738
Bos taurus	281201		BOVIN08465
Danio rerio	322104		DANRE43806
Canis lupus familiaris	403912		CANLF15746
Danio rerio	406796		DANRE37928
Pan troglodytes	469458		PANTR19703
Macaca mulatta	703399		MACMU23827