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glycoprotein Ib, beta polypeptide

Summary

Gene Symbol

Gp1bb

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

14724

PubChem

14724

Alliance of Genome Resources

MGI:107852

Annotation

Keyword

Blood coagulation
Cell adhesion
Disulfide bond
Glycoprotein
Leucine-rich repeat
Phosphoprotein
Proteomics identification
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B2RR03
P56400

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
cell adhesion	ISS	9259114
blood coagulation	IDA	18187573
blood coagulation, intrinsic pathway	ISO
blood coagulation, intrinsic pathway	NAS	23336709
positive regulation of platelet activation	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein maturation [inference]

protein activation cascade [inference]

blood coagulation, intrinsic pathway

primary metabolic process [inference]

protein metabolic process [inference]

protein maturation [inference]

protein activation cascade [inference]

blood coagulation, intrinsic pathway

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein maturation [inference]

protein activation cascade [inference]

blood coagulation, intrinsic pathway

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein maturation [inference]

protein activation cascade [inference]

blood coagulation, intrinsic pathway

cellular process [inference]

cell adhesion

cellular developmental process [inference]

cell development [inference]

hemopoiesis [inference]

myeloid cell development [inference]

megakaryocyte development

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

multicellular organismal process [inference]

coagulation [inference]

blood coagulation

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

hemopoiesis [inference]

myeloid cell development [inference]

megakaryocyte development

cellular developmental process [inference]

cell development [inference]

hemopoiesis [inference]

myeloid cell development [inference]

megakaryocyte development

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

organic substance transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of sequestering of calcium ion [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell activation [inference]

positive regulation of platelet activation

positive regulation of multicellular organismal process [inference]

positive regulation of cell activation [inference]

positive regulation of platelet activation

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of cell activation [inference]

positive regulation of platelet activation

negative regulation of cellular process [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol

regulation of cell activation [inference]

regulation of platelet activation [inference]

positive regulation of platelet activation

positive regulation of cell activation [inference]

positive regulation of platelet activation

regulation of sequestering of calcium ion [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of platelet activation [inference]

positive regulation of platelet activation

positive regulation of cell activation [inference]

positive regulation of platelet activation

positive regulation of multicellular organismal process [inference]

positive regulation of cell activation [inference]

positive regulation of platelet activation

regulation of biological quality [inference]

regulation of body fluid levels [inference]

hemostasis [inference]

blood coagulation

Displaying **all 3** entries
GO Term	Evidence Code	PMID
plasma membrane	ISS	9259114
glycoprotein Ib-IX-V complex	ISO
glycoprotein Ib-IX-V complex	NAS	23336709

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

glycoprotein Ib-IX-V complex

glycoprotein complex [inference]

glycoprotein Ib-IX-V complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

glycoprotein Ib-IX-V complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
identical protein binding	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

identical protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

leucine rich repeat

Functional Category

O: Posttranslational modification, protein turnover, chaperones
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Leucine-rich repeat domain superfamily
Leucine-rich repeat

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:2217	Bernard-Soulier syndrome	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 43 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	2812	Xenbase:XB-GENE-5829006	HUMAN59204
Xenopus tropicalis	14724	Xenbase:XB-GENE-5829006
Rattus norvegicus	116727		RATNO04039
Danio rerio	798998		DANRE43267
Sus scrofa	100155101		PIGXX07439
Taeniopygia guttata	100218998		TAEGU05806
Pongo abelii	100453789		PONAB22069
Cavia porcellus	100735782		CAVPO03527
Felis catus	101080743		FELCA28489
Octodon degus	101586597		OCTDE05736