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Guidelines

MIRAGE

cleavage stimulation factor subunit 3

Summary

Gene Symbol

CSTF3

Organism

Homo sapiens (human)

External Links

NCBI Gene

1479

PubChem

1479

Alliance of Genome Resources

HGNC:2485

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Nucleus
Phosphoprotein
Reference proteome
Repeat
mRNA processing

Proteins

Displaying 1 entry
UniProt	Protein Name
Q12996	CF-1 77 kDa subunit Cleavage stimulation factor 77 kDa subunit

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
RNA 3'-end processing	IBA
co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway	IDA	7984242

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

RNA 3'-end processing

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

RNA 3'-end processing

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

RNA 3'-end processing

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

RNA 3'-end processing

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

RNA 3'-end processing

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

RNA 3'-end processing

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

RNA 3'-end processing

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

RNA 3'-end processing

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

RNA 3'-end processing

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

RNA 3'-end processing

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

Displaying **all 4** entries
GO Term	Evidence Code	PMID
nucleus	IBA
nucleoplasm	TAS
nucleoplasm	IDA
mRNA cleavage stimulating factor complex	IDA	7984242

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

mRNA cleavage factor complex [inference]

mRNA cleavage stimulating factor complex

cellular anatomical entity [inference]

nucleoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 3** entries
GO Term	Evidence Code	PMID
RNA binding	HDA	22681889
mRNA binding	IBA
protein binding	IPI	7590244

GO Hierarchy

molecular function

binding [inference]

protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

mRNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

cleavage stimulation factor

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
RNA 3'-end processing
mRNA 3'-end processing

Displaying **all 4** entries
InterPro
HAT (Half-A-TPR) repeat
Suppressor of forked
Tetratricopeptide-like helical domain superfamily
mRNA 3'-end-processing protein Rna14-like

Ortholog

Displaying entries **1 - 10** of 76 in total

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Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	1479	Xenbase:XB-GENE-980297
Mus musculus	228410	Xenbase:XB-GENE-980297	MOUSE34315
Rattus norvegicus	362178		RATNO26278
Danio rerio	406326		DANRE14721
Pan troglodytes	451108		PANTR02602
Canis lupus familiaris	475948		CANLF05652
Bos taurus	508491		BOVIN07382
Macaca mulatta	694040		MACMU10198
Monodelphis domestica	100031302		MONDO27752
Equus caballus	100060162		HORSE06271

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025