GlyCosmos Portal

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GO Term	Evidence Code	PMID
magnesium ion binding	ISS
magnesium ion binding	ISO
glutathione synthase activity	ISO
glutathione synthase activity	IDA	8660701
glutathione synthase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

ligase activity [inference]

ligase activity, forming carbon-nitrogen bonds [inference]

acid-amino acid ligase activity [inference]

glutathione synthase activity

non-ribosomal peptide synthetase activity [inference]

glutathione synthase activity

binding [inference]

protein binding [inference]

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

amide binding [inference]

peptide binding

small molecule binding [inference]

organic acid binding [inference]

carboxylic acid binding [inference]

amino acid binding [inference]

glycine binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

amino acid binding [inference]

glycine binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

glutathione binding

cation binding [inference]

glycine binding

metal ion binding [inference]

magnesium ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Glutathione synthetase

Functional Category

I: Lipid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 7** entries
Gene Ontology
ATP binding
glutathione binding
glutathione biosynthetic process
glutathione synthase activity
ligase activity
metal ion binding
nucleotide binding

Displaying **all 7** entries
InterPro
Glutathione synthase, C-terminal, eukaryotic
Glutathione synthase, N-terminal, eukaryotic
Glutathione synthase, alpha-helical
Glutathione synthase, substrate-binding domain superfamily
Glutathione synthase, substrate-binding domain
Glutathione synthase
Pre-ATP-grasp domain superfamily

Ortholog

Displaying entries **1 - 10** of 82 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	2937		HUMAN56634
Xenopus tropicalis	14854	Xenbase:XB-GENE-976512
Rattus norvegicus	25458		RATNO25799
Canis lupus familiaris	442962		CANLF09480
Danio rerio	450084		DANRE47103
Bos taurus	525059		BOVIN05148
Macaca mulatta	706600		MACMU02467
Pan troglodytes	745328		PANTR24708
Monodelphis domestica	100032403		MONDO06843
Equus caballus	100069411		HORSE21585