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hypothetical protein

Summary

Gene Symbol

Organism

Variola virus

External Links

NCBI Gene: 1486427
PubChem: 1486427

Annotation

Keyword

Disulfide bond
Glycoprotein
Inhibition of host chemokines by virus
Reference proteome
Repeat
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P0DSV7	Viral tumor necrosis factor receptor II
P0DSV8	Viral tumor necrosis factor receptor II

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

1

2

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GO Term	Evidence Code	PMID
regulation of T cell cytokine production
intrinsic apoptotic signaling pathway in response to DNA damage
virus-mediated perturbation of host defense response
positive regulation of myelination
regulation of T cell proliferation

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

extrinsic apoptotic signaling pathway

intracellular signal transduction [inference]

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

apoptotic signaling pathway [inference]

extrinsic apoptotic signaling pathway

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

viral process [inference]

modulation by virus of host process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response

biological process involved in interspecies interaction between organisms [inference]

modulation of process of another organism [inference]

modulation by symbiont of host process [inference]

modulation by virus of host process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response

modulation by symbiont of host cellular process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

modulation by symbiont of host process [inference]

modulation by virus of host process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response

modulation by symbiont of host cellular process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

response to host [inference]

response to host defenses [inference]

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

response to other organism [inference]

response to defenses of other organism [inference]

response to host defenses [inference]

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

response to host [inference]

response to host defenses [inference]

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to defenses of other organism [inference]

response to host defenses [inference]

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

response to host [inference]

response to host defenses [inference]

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to defenses of other organism [inference]

response to host defenses [inference]

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

response to host [inference]

response to host defenses [inference]

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of leukocyte activation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation

regulation of immune effector process [inference]

regulation of production of molecular mediator of immune response [inference]

regulation of cytokine production involved in immune response [inference]

regulation of T cell cytokine production

regulation of leukocyte mediated immunity [inference]

regulation of lymphocyte mediated immunity [inference]

regulation of T cell mediated immunity [inference]

regulation of T cell cytokine production

regulation of immune response [inference]

regulation of adaptive immune response [inference]

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of T cell mediated immunity [inference]

regulation of T cell cytokine production

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

regulation of cytokine production involved in immune response [inference]

regulation of T cell cytokine production

regulation of production of molecular mediator of immune response [inference]

regulation of cytokine production involved in immune response [inference]

regulation of T cell cytokine production

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of cellular catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

regulation of cytokine production involved in immune response [inference]

regulation of T cell cytokine production

regulation of production of molecular mediator of immune response [inference]

regulation of cytokine production involved in immune response [inference]

regulation of T cell cytokine production

regulation of cellular catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

regulation of cytokine production involved in immune response [inference]

regulation of T cell cytokine production

regulation of production of molecular mediator of immune response [inference]

regulation of cytokine production involved in immune response [inference]

regulation of T cell cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of myelination

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system process [inference]

positive regulation of myelination

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

negative regulation of biological process [inference]

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response [inference]

negative regulation of neuroinflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response [inference]

negative regulation of neuroinflammatory response

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response [inference]

negative regulation of neuroinflammatory response

regulation of inflammatory response [inference]

negative regulation of inflammatory response [inference]

negative regulation of neuroinflammatory response

regulation of neuroinflammatory response [inference]

negative regulation of neuroinflammatory response

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response [inference]

negative regulation of neuroinflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response [inference]

negative regulation of neuroinflammatory response

regulation of immune response [inference]

regulation of adaptive immune response [inference]

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of T cell mediated immunity [inference]

regulation of T cell cytokine production

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response [inference]

negative regulation of neuroinflammatory response

regulation of inflammatory response [inference]

negative regulation of inflammatory response [inference]

negative regulation of neuroinflammatory response

regulation of neuroinflammatory response [inference]

negative regulation of neuroinflammatory response

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of glial cell differentiation [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of oligodendrocyte differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of myelination [inference]

positive regulation of myelination

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

extrinsic apoptotic signaling pathway

intracellular signal transduction [inference]

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

apoptotic signaling pathway [inference]

extrinsic apoptotic signaling pathway

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

regulation of cytokine production involved in immune response [inference]

regulation of T cell cytokine production

regulation of production of molecular mediator of immune response [inference]

regulation of cytokine production involved in immune response [inference]

regulation of T cell cytokine production

regulation of cellular catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of myelination [inference]

positive regulation of myelination

regulation of cell population proliferation [inference]

regulation of leukocyte proliferation [inference]

regulation of mononuclear cell proliferation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of glial cell differentiation [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of oligodendrocyte differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of myelination

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

regulation of cytokine production involved in immune response [inference]

regulation of T cell cytokine production

regulation of system process [inference]

regulation of nervous system process [inference]

positive regulation of nervous system process [inference]

positive regulation of myelination

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system process [inference]

positive regulation of myelination

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of myelination [inference]

positive regulation of myelination

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular region
extracellular space

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
tumor necrosis factor receptor activity
tumor necrosis factor binding

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

cytokine binding [inference]

tumor necrosis factor binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

death receptor activity [inference]

tumor necrosis factor receptor activity

Gene Ontology information from NCBI Gene and UniProt.

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Acknowledgements