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Guidelines

MIRAGE

heme oxygenase 2

Summary

Gene Symbol

Hmox2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

15369

PubChem

15369

Alliance of Genome Resources

MGI:109373

Annotation

Keyword

Acetylation
Heme
Microsome
Oxidoreductase
Phosphoprotein
Reference proteome
Repeat
S-nitrosylation
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
O70252
Q544R7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
response to hypoxia	ISO
response to hypoxia	IEA
heme oxidation	IBA
heme oxidation	IEA
response to oxidative stress	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

organonitrogen compound metabolic process [inference]

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

heme metabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

organonitrogen compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

catabolic process [inference]

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

cellular nitrogen compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

heterocycle catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

organonitrogen compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

pigment metabolic process [inference]

heme metabolic process [inference]

pigment catabolic process [inference]

heme catabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

aromatic compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

heme metabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

cellular nitrogen compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

heterocycle catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

heterocycle metabolic process [inference]

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

heme metabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

heterocycle catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

organic substance metabolic process [inference]

organic cyclic compound metabolic process [inference]

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

heme metabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

organic cyclic compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

organonitrogen compound metabolic process [inference]

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

heme metabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

organonitrogen compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

organonitrogen compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

aromatic compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

heme metabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

cellular nitrogen compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

heterocycle catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

heterocycle metabolic process [inference]

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

heme metabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

heterocycle catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

response to stimulus [inference]

response to stress [inference]

response to abiotic stimulus [inference]

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia

Displaying **all 3** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA
plasma membrane	ISO
plasma membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
heme oxygenase (decyclizing) activity	ISS
heme oxygenase (decyclizing) activity	ISO
heme oxygenase (decyclizing) activity	IBA
heme binding	IBA
metal ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

monooxygenase activity [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [inference]

heme oxygenase (decyclizing) activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [inference]

heme oxygenase (decyclizing) activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

tetrapyrrole binding [inference]

heme binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Heme oxygenase

Functional Category

H: Coenzyme transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
heme binding
heme catabolic process
heme oxidation
heme oxygenase (decyclizing) activity
metal ion binding
oxidoreductase activity
response to oxidative stress

Displaying **all 4** entries
InterPro
Haem oxygenase conserved site
Haem oxygenase-like, multi-helical
Haem oxygenase-like
Haem oxygenase

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026