hypoxanthine phosphoribosyltransferase 1
| UniProt | Protein Name |
|---|---|
| P00493 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| T cell mediated cytotoxicity | ||
| response to amphetamine | ||
| purine nucleotide biosynthetic process | ||
| purine ribonucleoside salvage | ||
| purine ribonucleoside salvage |
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleotide binding | ||
| magnesium ion binding | ||
| magnesium ion binding | ||
| magnesium ion binding | ||
| hypoxanthine phosphoribosyltransferase activity |
| Gene Ontology |
|---|
| GMP salvage |
| IMP salvage |
| guanine phosphoribosyltransferase activity |
| guanine salvage |
| hypoxanthine metabolic process |
| hypoxanthine phosphoribosyltransferase activity |
| magnesium ion binding |
| metal ion binding |
| nucleotide binding |
| purine ribonucleoside salvage |
| InterPro |
|---|
| Hypoxanthine phosphoribosyl transferase |
| Phosphoribosyltransferase domain |
| Phosphoribosyltransferase-like |
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1919 | Lesch-Nyhan syndrome |
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 101053337 | SAIBB18644 | ||
| 101095235 | FELCA38769 | ||
| 101109657 | SHEEP00217 | ||
| 101131143 | GORGO43148 | ||
| 101163340 | ORYLA01437 | ||
| 101574393 | OCTDE11027 | ||
| 101678157 | MUSPF02259 | ||
| 101955334 | ICTTR01046 | ||
| 102183404 | CAPHI31190 | ||
| 102354389 | LATCH17467 |
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Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: December 8, 2025