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hydroxysteroid (17-beta) dehydrogenase 7

Summary

Gene Symbol

Hsd17b7

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

15490

PubChem

15490

Alliance of Genome Resources

MGI:1330808

Annotation

Keyword

Endoplasmic reticulum
Glycoprotein
NAD
NADP
Oxidoreductase
Reference proteome
Steroid biosynthesis
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
O88736	17-beta-hydroxysteroid dehydrogenase 7 3-keto-steroid reductase Dihydrotestosterone oxidoreductase Estradiol 17-beta-dehydrogenase 7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
cholesterol biosynthetic process	ISO
cholesterol biosynthetic process	IDA	12829805
cholesterol biosynthetic process	IBA
estrogen biosynthetic process	ISO
estrogen biosynthetic process	IDA	12732193 9658408

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

hormone biosynthetic process [inference]

estrogen biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

hormone metabolic process [inference]

androgen metabolic process

estrogen metabolic process [inference]

estrogen biosynthetic process

hormone biosynthetic process [inference]

estrogen biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

androgen metabolic process

estrogen metabolic process [inference]

estrogen biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

secondary alcohol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

androgen metabolic process

estrogen metabolic process [inference]

estrogen biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

androgen metabolic process

estrogen metabolic process [inference]

estrogen biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

secondary alcohol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

cellular process [inference]

cellular developmental process [inference]

cell differentiation

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

system development [inference]

skeletal system development [inference]

embryonic skeletal system development

nervous system development

cellular developmental process [inference]

cell differentiation

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

androgen metabolic process

estrogen metabolic process [inference]

estrogen biosynthetic process

hormone biosynthetic process [inference]

estrogen biosynthetic process

Displaying **all 4** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum	IDA	12829805
endoplasmic reticulum membrane	ISO
endoplasmic reticulum membrane	IDA	12829805
endoplasmic reticulum membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
3-keto sterol reductase activity	ISO
3-keto sterol reductase activity	IDA	12829805
3-keto sterol reductase activity	IBA
estradiol 17-beta-dehydrogenase [NAD(P)] activity	ISO
estradiol 17-beta-dehydrogenase [NAD(P)] activity	IDA	12732193 9658408

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

steroid dehydrogenase activity [inference]

steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

3-keto sterol reductase activity

steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

cytokine receptor binding [inference]

prolactin receptor binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **1 - 10** of 70 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	15490	Xenbase:XB-GENE-976825
Rattus norvegicus	29540	Xenbase:XB-GENE-976825	RATNO07324
Homo sapiens	51478	Xenbase:XB-GENE-976825	HUMAN53346
Pan troglodytes	466046		PANTR22870
Bos taurus	505212		BOVIN25485
Canis lupus familiaris	609364		CANLF14387
Macaca mulatta	720399		MACMU23605
Pan troglodytes	747814		PANTR22870
Danio rerio	768185		DANRE37893
Monodelphis domestica	100016071		MONDO12299