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cytochrome P450 family 2 subfamily B member 6
Summary
- Gene Symbol
-
- CYP2B6
- Aliases
-
- CPB6
- CYPIIB6
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Heme
- Lipid metabolism
- Membrane
- Microsome
- Monooxygenase
- NADP
- Phosphoprotein
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| P20813 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| epoxygenase P450 pathway | ||
| xenobiotic catabolic process | ||
| cellular ketone metabolic process | ||
| steroid metabolic process | ||
| xenobiotic metabolic process |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| intracellular membrane-bounded organelle | ||
| cytoplasm | ||
| endoplasmic reticulum membrane |
|
GO Hierarchy
GO Hierarchy
molecular function
catalytic activity [inference]
oxidoreductase activity [inference]
monooxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
KEGG BRITE Database
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060891 | Parkinson's disease 19A | |
| DOID:0060895 | Parkinson's disease 4 | |
| DOID:0060896 | Parkinson's disease 23 | |
| DOID:0070322 | childhood hepatocellular carcinoma | |
| DOID:0070328 | adult hepatocellular carcinoma | |
| DOID:0080067 | Charcot-Marie-Tooth disease type 5 | |
| DOID:0080144 | childhood acute lymphocytic leukemia | |
| DOID:0080162 | lupus nephritis | |
| DOID:0080199 | colorectal carcinoma | |
| DOID:0080348 | Alzheimer's disease 1 |
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP000449
- Gene Name
- cytochrome P450, family 2, subfamily B, polypeptide 6
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 178695 | WB:WBGene00016697 | ||
| 178704 | WB:WBGene00018413 | ||
| 178803 | WB:WBGene00019472 | ||
| 179148 | WB:WBGene00015709 | ||
| 181850 | WB:WBGene00015043 | ||
| 181851 | WB:WBGene00015044 | ||
| 181852 | WB:WBGene00015045 | ||
| 182176 | WB:WBGene00015399 | ||
| 182177 | WB:WBGene00015400 | ||
| 182888 | WB:WBGene00016092 |
