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Envelope surface glycoprotein gp160, precursor

Summary

Gene Symbol

Organism

Human immunodeficiency virus 1

External Links

NCBI Gene: 155971
PubChem: 155971

Annotation

Keyword

3D-structure
AIDS
Apoptosis
Clathrin-mediated endocytosis of virus by host
Cleavage on pair of basic residues
Coiled coil
Disulfide bond
Fusion of virus membrane with host endosomal membrane
Glycoprotein
Host cell membrane
Host endosome
Palmitate
Reference proteome
Signal
Transmembrane helix
Viral attachment to host cell
Viral envelope protein
Viral immunoevasion

Proteins

Displaying 1 entry
UniProt	Protein Name
P04578	Env polyprotein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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3

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GO Term	Evidence Code	PMID
apoptotic process
actin filament organization
virus-mediated perturbation of host defense response
virion attachment to host cell
fusion of virus membrane with host plasma membrane

GO Hierarchy

biological process

cellular process [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor-mediated endocytosis of virus by host cell [inference]

clathrin-dependent endocytosis of virus by host cell

clathrin-dependent endocytosis [inference]

clathrin-dependent endocytosis of virus by host cell

endocytosis involved in viral entry into host cell [inference]

receptor-mediated endocytosis of virus by host cell [inference]

clathrin-dependent endocytosis of virus by host cell

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization [inference]

membrane fusion [inference]

fusion of virus membrane with host plasma membrane

supramolecular fiber organization [inference]

actin filament organization

viral process [inference]

modulation by virus of host process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response

viral protein processing

membrane fusion involved in viral entry into host cell [inference]

transport of virus [inference]

endocytosis involved in viral entry into host cell [inference]

receptor-mediated endocytosis of virus by host cell [inference]

clathrin-dependent endocytosis of virus by host cell

biological process involved in interspecies interaction between organisms [inference]

modulation of process of another organism [inference]

modulation by symbiont of host process [inference]

modulation by virus of host process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response

modulation by symbiont of host cellular process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

entry into host [inference]

viral entry into host cell

modulation by symbiont of host process [inference]

modulation by virus of host process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response

modulation by symbiont of host cellular process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

adhesion of symbiont to host [inference]

adhesion of symbiont to host cell [inference]

virion attachment to host cell

response to host [inference]

response to host defenses [inference]

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

response to other organism [inference]

response to defenses of other organism [inference]

response to host defenses [inference]

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

response to host [inference]

response to host defenses [inference]

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to defenses of other organism [inference]

response to host defenses [inference]

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

response to host [inference]

response to host defenses [inference]

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to defenses of other organism [inference]

response to host defenses [inference]

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

response to host [inference]

response to host defenses [inference]

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor-mediated endocytosis of virus by host cell [inference]

clathrin-dependent endocytosis of virus by host cell

clathrin-dependent endocytosis [inference]

clathrin-dependent endocytosis of virus by host cell

endocytosis involved in viral entry into host cell [inference]

receptor-mediated endocytosis of virus by host cell [inference]

clathrin-dependent endocytosis of virus by host cell

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor-mediated endocytosis of virus by host cell [inference]

clathrin-dependent endocytosis of virus by host cell

clathrin-dependent endocytosis [inference]

clathrin-dependent endocytosis of virus by host cell

endocytosis involved in viral entry into host cell [inference]

receptor-mediated endocytosis of virus by host cell [inference]

clathrin-dependent endocytosis of virus by host cell

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of establishment of T cell polarity

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of establishment of T cell polarity

regulation of lymphocyte activation [inference]

regulation of T cell activation [inference]

positive regulation of T cell activation [inference]

positive regulation of establishment of T cell polarity

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of establishment of T cell polarity

regulation of localization [inference]

regulation of cellular localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to membrane [inference]

positive regulation of receptor clustering

regulation of protein localization to membrane [inference]

regulation of receptor clustering [inference]

positive regulation of receptor clustering

positive regulation of protein localization to membrane [inference]

positive regulation of receptor clustering

regulation of plasma membrane raft polarization [inference]

positive regulation of plasma membrane raft polarization

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of establishment of T cell polarity

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of establishment of T cell polarity

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of establishment of T cell polarity

positive regulation of cellular component organization [inference]

positive regulation of plasma membrane raft polarization

positive regulation of protein localization [inference]

positive regulation of protein localization to membrane [inference]

positive regulation of receptor clustering

positive regulation of multicellular organismal process [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of establishment of T cell polarity

regulation of cellular process [inference]

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of establishment of T cell polarity

regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of establishment of T cell polarity

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of establishment of T cell polarity

regulation of establishment or maintenance of cell polarity [inference]

regulation of establishment of cell polarity [inference]

regulation of establishment of T cell polarity [inference]

positive regulation of establishment of T cell polarity

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of establishment of T cell polarity

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of establishment of T cell polarity

positive regulation of cellular component organization [inference]

positive regulation of plasma membrane raft polarization

positive regulation of protein localization [inference]

positive regulation of protein localization to membrane [inference]

positive regulation of receptor clustering

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of establishment of T cell polarity

regulation of lymphocyte activation [inference]

regulation of T cell activation [inference]

positive regulation of T cell activation [inference]

positive regulation of establishment of T cell polarity

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of establishment of T cell polarity

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of establishment of T cell polarity

regulation of cellular component organization [inference]

positive regulation of cellular component organization [inference]

positive regulation of plasma membrane raft polarization

regulation of plasma membrane organization [inference]

regulation of plasma membrane raft polarization [inference]

positive regulation of plasma membrane raft polarization

regulation of cellular localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to membrane [inference]

positive regulation of receptor clustering

regulation of protein localization to membrane [inference]

regulation of receptor clustering [inference]

positive regulation of receptor clustering

positive regulation of protein localization to membrane [inference]

positive regulation of receptor clustering

regulation of plasma membrane raft polarization [inference]

positive regulation of plasma membrane raft polarization

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of establishment of T cell polarity

regulation of lymphocyte activation [inference]

regulation of T cell activation [inference]

positive regulation of T cell activation [inference]

positive regulation of establishment of T cell polarity

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of establishment of T cell polarity

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of establishment of T cell polarity

positive regulation of multicellular organismal process [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of establishment of T cell polarity

Displaying **all 5** entries
GO Term	Evidence Code	PMID
membrane
viral envelope
host cell plasma membrane
host cell endosome membrane
virion membrane

GO Hierarchy

cellular component

virion component [inference]

viral membrane [inference]

viral envelope

virion membrane

cellular anatomical entity [inference]

membrane

host cellular component [inference]

host cell part [inference]

host cell membrane [inference]

Displaying 1 entry
GO Term	Evidence Code	PMID
structural molecule activity

GO Hierarchy

molecular function

structural molecule activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level: Viruses
Group Name: Human immunodeficiency virus 1, envelope glycoprotein Gp120

Displaying **all 3** entries
Gene Ontology
membrane fusion involved in viral entry into host cell
structural molecule activity
virion attachment to host cell

Displaying **all 3** entries
InterPro
Gp120 core superfamily
Human immunodeficiency virus 1, envelope glycoprotein Gp120
Retroviral envelope protein GP41-like

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements